X0306 4 2016-01-22 0 0001217234 CareDx, Inc. CDNA 0001630732 Sninsky John Joseph C/O CAREDX, INC. 3260 BAYSHORE BOULEVARD BRISBANE CA 94005 0 1 0 0 Chief Scientific Officer Common Stock 2016-01-22 4 A 0 11000 0.00 A 14000 D Employee Stock Option (right to buy) 5.27 2016-01-22 4 A 0 33000 0.00 A 2026-01-22 Common Stock 33000 33000 D The reported securities are represented by restricted stock units 1/4th of which shall vest on January 22, 2017 and 1/4th of which shall vest on each yearly anniversary thereafter. Includes 3,000 shares that Reporting Person acquired pursuant to Issuer's 2014 Employee Stock Purchasing Plan. Reporting Person acquired 2,459 shares on June 30, 2015 and 541 shares on December 31, 2015. 1/4th of the shares subject to the option shall vest on January 22, 2017 and 1/48th of the shares subject to the option shall vest monthly thereafter. /s/ Kenneth Ludlum, by power of attorney 2016-01-26