May 3, 2024

Office of Life Sciences

Division of Corporation Finance

U.S. Securities and Exchange Commission

100 F Street, NE

Washington, D.C. 20549

Re: REQUEST FOR ACCELERATION OF EFFECTIVENESS

Dyadic International, Inc. (CIK No. 0001213809)

Registration Statement on Form S-3

File No. 333-278916

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, Dyadic International, Inc. (the “Company”), hereby requests that the effective date of the Company’s Registration Statement on Form S-3 (File No. 333-278916) (the “Registration Statement”) be accelerated by the Securities and Exchange Commission so that the Registration Statement will become effective at 4:00 p.m., Eastern Daylight Time, on May 7, 2024, or as soon as practicable thereafter.

Should you have any questions regarding this letter, please do not hesitate to contact Kimberly Petillo-Decossard at (212) 819-8398 or Jessica Y. Chen at (212) 819-8503 of White & Case LLP, counsel to the Company.

	Sincerely yours,
	Dyadic International, Inc.
By:	/s/ Ping Rawson
	Name: Ping Rawson
	Title: Chief Financial Officer