Note 5 - Share-based Compensation (Tables)

6 Months Ended

Jun. 30, 2023

Notes Tables

Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

Risk-Free interest rate	3.90% - 5.12%
Expected dividend yield	—%
Expected stock price volatility	62.22%-64.27%
Expected life of options (in years)	1.13- 6.25

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

						Weighted-Average
				Weighted-Average		Remaining Contractual		Aggregate Intrinsic
	Shares			Exercise Price		Term (Years)		Value
Outstanding at December 31, 2022		5,031,097		$	3.25		5.75	$	13,000
Granted (1)		745,350			1.43
Exercised		—			—
Expired (2)		(320,000	)		1.62
Canceled		—			—
Outstanding at June 30, 2023		5,456,447		$	3.10		6.12	$	1,011,183
Exercisable at June 30, 2023		4,179,293		$	3.15		5.32	$	621,865

Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]

				Weighted-Average
				Grant Date
	Shares			Fair Value
Outstanding at December 31, 2022		—		$	—
Granted (1)		411,005			1.38
Vested (1)		(247,961	)		1.38
Outstanding at June 30, 2023		163,044		$	1.38

Share-Based Payment Arrangement, Activity [Table Text Block]

	Three Months Ended June 30,				Six Months Ended June 30,
	2023		2022		2023		2022
General and administrative	$	323,796	$	389,885	$	643,132	$	778,548
Research and development		10,520		64,615		21,823		129,743
Total	$	334,316	$	454,500	$	664,955	$	908,291

	Three Months Ended June 30,				Six Months Ended June 30,
	2023		2022		2023		2022
Share based compensation expense- stock options	$	278,373	$	454,500	$	554,914	$	908,291
Share based compensation expense- restricted stock units		55,943		—		110,041		—
Total	$	334,316	$	454,500	$	664,955	$	908,291