Note 1 - Organization and Summary of Significant Accounting Policies - Research and Development Costs (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Outside contracted services	$ 643,047	$ 1,135,556
Personnel related costs	152,194	206,790
Facilities, overhead and other	15,325	516
Research And Development Expense, Including Related Party	$ 810,566	$ 1,342,862