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Note 1 - Organization and Summary of Significant Accounting Policies - Accrued Expenses (Details) - USD ($)
Mar. 31, 2023
Dec. 31, 2022
Research and development expenses $ 588,739 $ 580,264
Employee wages and benefits 187,026 343,457
Other 87,276 31,360
Accrued Liabilities, Current $ 863,041 $ 955,081