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Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Operating activities    
Net loss $ (16,414,159) $ (16,461,178)
Adjustments to reconcile net loss to net cash used in operating activities:    
Loss on disposal of assets 0 362,949
Impairment loss 0 187,500
Depreciation and amortization 494,232 859,487
Stock-based compensation expense 884,943 2,174,627
Gain on extinguishment of debt 0 (17,974)
Deferred rent 0 59,206
Change in fair value of derivative financial instruments—warrants (28,188) (617,072)
Release of clinical trial funding commitment 703,327 0
Changes in operating assets and liabilities:    
Other assets (54,778) (23,755)
Accounts receivable and unbilled receivable (35,725) 19,262
Prepaid expenses 115,459 21,451
Operating lease right-of-use assets 302,491 0
Accounts payable and accrued expenses 1,455,336 214,484
Operating lease liabilities (776,806) 0
Other liabilities 86,368 22,000
Net cash used in operating activities (13,267,500) (13,199,013)
Investing activities    
Capital expenditures (67,622) (5,100)
Proceeds from disposals of capital equipment 0 27,942
Purchases of short-term investments 0 (31,500)
Sales of short-term investments 0 31,500
Net cash provided (used) by investing activities (67,622) 22,842
Financing activities    
Proceeds from sale of common stock and warrants, net of expenses of $158,678 and $1,336,123 respectively 8,817,772 11,779,525
Proceeds from sales of Series B Convertible Preferred Stock, net of expenses of $0 and $497,617 respectively 0 4,386,762
Costs related to the clinical trial funding commitment (40,000) 0
Proceeds from exercise of warrants 3,299,509 1,612,667
Repayments under equipment line of credit 0 (1,200,033)
Payment upon debt extinguishment 0 (175,381)
Net cash provided by financing activities 12,077,281 16,403,540
Net change in cash and cash equivalents (1,257,841) 3,227,369
Cash and cash equivalents—Beginning of period 11,453,133 8,225,764
Cash and cash equivalents—End of period 10,195,292 11,453,133
Supplementary disclosure of cash flow activity:    
Cash paid for taxes 800 800
Cash paid for interest 0 22,482
Supplemental disclosure of non-cash investing and financing activities:    
Preferred stock dividend payable on Series A Convertible Preferred Stock 24,240 24,240
Common stock, Series C Convertible Preferred Stock and warrants issued in connection with clinical trial funding commitment, net of discount of $235,640 1,675,000 0
Series B Convertible Preferred Stock    
Supplemental disclosure of non-cash investing and financing activities:    
Deemed dividend recognized on beneficial conversion features of convertible preferred stock 0 2,769,533
Common stock issued upon conversion of Convertible Preferred Stock 0 886
Series C Convertible Preferred Stock    
Supplemental disclosure of non-cash investing and financing activities:    
Deemed dividend recognized on beneficial conversion features of convertible preferred stock 268,269 0
Common stock issued upon conversion of Convertible Preferred Stock $ 33 $ 0