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Statements of Stockholders' Equity - USD ($)
Total
Preferred Stock
Common Stock
Additional Paid-In Capital
Service Receivable
Accumulated Deficit
Balance (in shares) at Dec. 31, 2017   60,600 733,217      
Balance at Dec. 31, 2017 $ 6,506,107 $ 60 $ 5,279 $ 179,546,954 $ 0 $ (173,046,186)
Increase (Decrease) in Stockholders' Equity            
Sale of common stock and warrants, net of expenses (in shares)     1,523,333      
Sale of common stock and warrants, net of expenses 11,779,525   $ 914 11,778,611    
Sale of stock, net of expenses (in shares)   8,860        
Sale of Series B Convertible Preferred Stock, net of expenses 4,386,762 $ 9   4,386,753    
Stock-based compensation 2,174,627     2,174,627    
Issuance of common stock upon exercise of warrants (in shares)     78,917      
Issuance of common stock upon exercise of warrants 1,612,667   $ 569 1,612,098    
Issuance of common stock upon vesting of restricted stock awards (in shares)     18,609      
Issuance of common stock upon vesting of restricted stock awards 0   $ 94 (94)    
Deemed dividend recognized on beneficial conversion features of Series B Convertible Preferred Stock issuance 0     2,769,533   (2,769,533)
Issuance of common stock upon conversion of Series B Convertible Preferred Stock (in shares)   (8,860) 1,476,667      
Issuance of common stock upon conversion of Convertible Preferred Stock 0 $ (9) $ 886 (877)    
Preferred stock dividend payable on Series A Convertible Preferred Stock (24,240)         (24,240)
Issuance of common stock for share rounding as a result of reverse stock split (in shares)     1,136      
Cumulative effect of change in accounting principle related to revenue recognition 109,922         109,922
Net loss (16,461,178)         (16,461,178)
Balance (in shares) at Dec. 31, 2018   60,600 3,831,879      
Balance at Dec. 31, 2018 10,084,192 $ 60 $ 7,742 202,267,605 0 (192,191,215)
Increase (Decrease) in Stockholders' Equity            
Sale of common stock and warrants, net of expenses (in shares)     1,994,929      
Sale of common stock and warrants, net of expenses $ 8,817,772   $ 199 8,817,573    
Sale of stock, net of expenses (in shares) 1,994,929   4,761,754      
Stock-based compensation $ 884,942     884,942    
Issuance of common stock upon exercise of warrants (in shares)     2,221,635      
Issuance of common stock upon exercise of warrants 3,299,510   $ 223 3,299,287    
Issuance of common stock upon vesting of restricted stock awards (in shares)     22,057      
Issuance of common stock upon vesting of restricted stock awards 0   $ 5 (5)    
Issuance of common stock upon conversion of Series B Convertible Preferred Stock (in shares)   (200,000) 333,333      
Issuance of common stock upon conversion of Convertible Preferred Stock 0 $ (200) $ 33 167    
Preferred stock dividend payable on Series A Convertible Preferred Stock (24,240)         (24,240)
Issuance of common stock for share rounding as a result of reverse stock split (in shares)     6,466      
Net loss (16,414,159)         (16,414,159)
Issuance of common stock, preferred stock and warrants for clinical trial funding commitment, net of expenses and discount (in shares)   200,000 183,334      
Issuance of common stock, preferred stock and warrants for clinical trial funding commitment, net of expenses and discount (40,000) $ 200 $ 110 1,634,690 (1,675,000)  
Deemed dividend recognized on beneficial conversion features of Series C Convertible Preferred Stock issuance 0     268,269   (268,269)
Release of clinical trial funding commitment 703,327       703,327  
Balance (in shares) at Dec. 31, 2019   60,600 8,593,633      
Balance at Dec. 31, 2019 $ 7,311,344 $ 60 $ 8,312 $ 217,172,528 $ (971,673) $ (208,897,883)