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Stockholders' Equity - Stock Option Activity (Details) - USD ($)
6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 06, 2019
Jun. 05, 2019
Dec. 31, 2018
Stock Option          
Weighted-average assumptions          
Risk-free interest rate 1.80% 2.43%      
Dividend yield (as a percent) 0.00% 0.00%      
Expected volatility (as a percent) 95.00% 90.00%      
Expected term 5 years 10 months 24 days 5 years 2 months 23 days      
Number of Options          
Balance outstanding at the beginning of the period (in shares) 83,345        
Granted (in shares) 961,313        
Cancelled / Forfeited (in shares) (11,384)        
Balance outstanding at the end of the period (in shares) 1,033,274        
Exercisable at the end of the period (in shares) 74,486        
Weighted Average Exercise Price Per Share          
Balance outstanding at the beginning of the period (in USD per share) $ 146.09        
Granted (in USD per share) 2.50        
Canceled / Forfeited (in USD per share) 70.82        
Balance outstanding at the end of the period (in USD per share) 13.34        
Exercisable at the end of the period (in USD per share) $ 149.43        
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures          
Options outstanding, intrinsic value $ 19,059       $ 0
Vested and exercisable at the end of the period, intrinsic value $ 0        
2014 EIP          
Share-based Compensation Arrangement by Share-based Payment Award, Options, Additional Disclosures          
Authorized shares under the plan (in shares)     1,243,056 243,056  
Number of remaining shares available for issuance (in shares) 161,500