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Stockholders' Equity (Tables)
6 Months Ended
Jun. 30, 2019
Stockholders' Equity Note [Abstract]  
Schedule of Stock-Based Compensation Expense
Stock-based compensation expense related to Trovagene equity awards have been recognized in operating results as follows:
 
 
Three Months Ended June 30,
 
Six Months Ended June 30,
 
2019
 
2018
 
2019
 
2018
Included in cost of revenue
$

 
$
(9,143
)
 
$

 
$
30,488

Included in research and development expense
$
86,058

 
$
111,812

 
$
196,139

 
$
507,521

Included in selling, general and administrative expense
62,776

 
118,631

 
152,763

 
1,089,422

Total stock-based compensation expense
$
148,834

 
$
221,300

 
$
348,902

 
$
1,627,431

Schedule of Assumptions to Estimate Fair Value of Stock Option Awards
The estimated fair value of stock option awards was determined on the date of grant using the Black-Scholes option valuation model with the following weighted-average assumptions during the following periods indicated:
 
 
Six Months Ended June 30,
 
2019
 
2018
Risk-free interest rate
1.8
%
 
2.43
%
Dividend yield
0
%
 
0
%
Expected volatility
95
%
 
90
%
Expected term
5.9 years

 
5.2 years



Summary of Stock Option Activity and of Changes in Stock Options Outstanding
A summary of stock option activity and changes in stock options outstanding is presented below:
 
 
Total Options
 
Weighted-Average
Exercise Price
Per Share
 
Intrinsic
Value
Balance outstanding, December 31, 2018
83,345

 
$
146.09

 
$

Granted
961,313

 
$
2.50

 
 

Canceled / Forfeited
(11,384
)
 
$
70.82

 
 

Balance outstanding, June 30, 2019
1,033,274

 
$
13.34

 
$
19,059

Exercisable at June 30, 2019
74,486

 
$
149.43

 
$

Schedule of Share-based Compensation, Restricted Stock and Restricted Stock Units Activity
A summary of the RSU activity is presented below:
 
Number of Shares
 
Weighted-Average
Grant Date Fair Value
Per Share
 
Intrinsic Value
Non-vested RSUs outstanding, December 31, 2018
30,132

 
$
14.36

 
$
95,005

Granted
167

 
$
4.04

 
 
Vested
(10,795
)
 
$
13.67

 
$
41,233

Forfeited
(5,317
)
 
$
13.04

 
 
Non-vested RSUs outstanding, June 30, 2019
14,187

 
$
15.25

 
$
35,468

Summary of Warrant Activity and Changes in Warrants Outstanding
A summary of warrant activity and changes in warrants outstanding, including both liability and equity classifications is presented below:
 
 
Total Warrants
 
Weighted-Average
Exercise Price
Per Share
 
Weighted-Average
Remaining Contractual
Term
Balance outstanding, December 31, 2018
3,649,341

 
$
8.91

 
4.4
Granted
1,408,510

 
$
3.50

 
 
Exercised
(653,666
)
 
$
5.96

 
 
Balance outstanding, June 30, 2019
4,404,185

 
$
7.62

 
4.3