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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Income Statement [Abstract]        
Royalties $ 58,779 $ 47,236 $ 169,415 $ 207,869
Diagnostic services 58,119 37,978 142,482 69,558
Clinical research services 6,431 3,900 8,481 35,573
Total revenues 123,329 89,114 320,378 313,000
Costs and expenses:        
Cost of revenues 473,202 424,559 1,427,831 1,143,293
Research and development 1,414,706 3,937,398 6,676,251 11,221,876
Selling and marketing 419,927 2,940,862 2,442,931 9,127,450
General and administrative 3,659,587 2,710,782 9,915,359 9,183,761
Restructuring Charges (46,472) 0 1,669,526 0
Total operating expenses 5,920,950 10,013,601 22,131,898 30,676,380
Loss from operations (5,797,621) (9,924,487) (21,811,520) (30,363,380)
Net interest expense (16,473) (354,993) (877,741) (967,522)
Gain from change in fair value of derivative financial instruments—warrants 1,528,669 88,208 2,012,747 674,834
Loss on extinguishment of debt 0 0 (1,655,825) 0
Other loss, net (6,541) 0 (4,975) 0
Net loss (4,291,966) (10,191,272) (22,337,314) (30,656,068)
Preferred stock dividend (6,060) (6,060) (18,180) (18,180)
Net loss attributable to common stockholders $ (4,298,026) $ (10,197,332) $ (22,355,494) $ (30,674,248)
Net loss per common share - basic (in USD per share) $ (0.12) $ (0.34) $ (0.68) $ (1.02)
Net loss per common share - diluted (in USD per share) $ (0.12) $ (0.34) $ (0.68) $ (1.04)
Weighted-average shares outstanding — basic 36,465,672 30,339,774 32,826,306 30,018,841
Weighted-average shares outstanding — diluted 36,465,672 30,339,774 32,826,306 30,136,572