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- Loan and Security Agreement (Details) - USD ($)
1 Months Ended 3 Months Ended
Jul. 20, 2016
Jun. 30, 2014
Nov. 30, 2015
Mar. 31, 2017
Dec. 31, 2016
Debt Instrument [Line Items]          
Amount borrowed included in current liabilities       $ 3,873,438 $ 2,360,109
Amount borrowed, long-term liabilities       $ 12,699,739 $ 14,176,359
Loan and Security Agreement          
Debt Instrument [Line Items]          
Interest rate at end of period       5.25%  
Accrued final payment       $ 41,030  
Interest expenses recorded       30,267  
Future minimum principal payments          
Plus final fee premium accretion       41,030  
Total long-term obligations       1,710,641  
Prime Rate | Loan and Security Agreement          
Debt Instrument [Line Items]          
Interest above base rate     1.25%    
Secured Debt          
Debt Instrument [Line Items]          
Face value of term loan   $ 15,000,000      
Number of common shares that can be purchased upon exercise of warrant   85,470      
Exercise price of warrants (in USD per share)   $ 3.51      
Exercisable term of warrant   10 years      
Amortized portion of final fee upon repayment       1,125,000  
Amount borrowed included in current liabilities       3,247,334  
Current portion of debt discount       252,666  
Amount borrowed, long-term liabilities       11,615,202  
Accrued final payment       308,654  
Interest expenses recorded       465,956  
Future minimum principal payments          
2018       3,500,000  
2019       6,000,000  
2020       5,500,000  
Total principal       15,000,000  
Less discount       (446,118)  
Plus final fee premium accretion       308,654  
Total long-term obligations       $ 14,862,536  
Secured Debt | Minimum          
Debt Instrument [Line Items]          
Pre-payment fees (as a percent)       1.00%  
Secured Debt | Maximum          
Debt Instrument [Line Items]          
Pre-payment fees (as a percent)       3.00%  
Secured Debt | Loan and Security Agreement          
Debt Instrument [Line Items]          
Number of common shares that can be purchased upon exercise of warrant 30,992 42,735   73,727  
Exercise price of warrants (in USD per share) $ 4.84        
Exercisable term of warrant 10 years        
Interest rate at end of period       7.75%  
Value of warrants recorded as debt discount and additional paid in capital       $ 148,885  
Secured Debt | Loan and Security Agreement | Minimum          
Debt Instrument [Line Items]          
Debt instrument stated rate 7.25%        
Secured Debt | Prime Rate | Loan and Security Agreement          
Debt Instrument [Line Items]          
Interest above base rate 3.75%