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Summary of Significant Accounting Policies - Antidilutive Securities (Details) - shares
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Net Loss Per Share    
Antidilutive securities excluded from the calculation of basic and diluted loss per share (in shares) 11,233,583 12,696,096
Stock Option    
Net Loss Per Share    
Antidilutive securities excluded from the calculation of basic and diluted loss per share (in shares) 4,687,566 8,117,024
Warrants    
Net Loss Per Share    
Antidilutive securities excluded from the calculation of basic and diluted loss per share (in shares) 5,505,901 4,515,947
Restricted Stock Units (RSUs)    
Net Loss Per Share    
Antidilutive securities excluded from the calculation of basic and diluted loss per share (in shares) 976,991 0
Series A Convertible Preferred Stock    
Net Loss Per Share    
Antidilutive securities excluded from the calculation of basic and diluted loss per share (in shares) 63,125 63,125