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Commitments and Contingencies (Details) (USD $)
3 Months Ended 9 Months Ended 170 Months Ended 9 Months Ended 9 Months Ended 0 Months Ended 1 Months Ended 1 Months Ended 0 Months Ended 8 Months Ended 1 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Dec. 31, 2012
Sep. 30, 2013
Stock options
Sep. 30, 2013
Research and Development Agreements
MDACC
Dec. 31, 2012
Research and Development Agreements
MDACC
Sep. 30, 2013
Research and Development Agreements
PerkinElmer Health Sciences, Inc.
Apr. 25, 2013
Research and Development Agreements
PerkinElmer Health Sciences, Inc.
HCC Field
Apr. 25, 2013
Research and Development Agreements
PerkinElmer Health Sciences, Inc.
Other fields
Jun. 30, 2013
Research and Development Agreements
Illumina
Aug. 31, 2013
Research and Development Agreements
USC
Jan. 31, 2013
Employment agreement with Mark Erlander, Ph.D.
Jan. 31, 2013
Employment agreement with Mark Erlander, Ph.D.
Maximum
Jan. 31, 2013
Employment agreement with Mark Erlander, Ph.D.
Stock options
Jul. 31, 2013
Public Offering and Controlled Equity Offering
Jan. 25, 2013
Public Offering and Controlled Equity Offering
Maximum
Jan. 25, 2013
Public Offering and Controlled Equity Offering
Agent
Sep. 30, 2013
Public Offering and Controlled Equity Offering
Agent
Jan. 25, 2013
Public Offering and Controlled Equity Offering
Agent
Maximum
Jun. 30, 2013
CFO
Jun. 30, 2013
CFO
Stock options
Jun. 30, 2013
CEO
Jun. 30, 2013
CEO
Stock options
Commitments and contingencies                                                    
Amount committed to be paid                 $ 152,900         $ 232,000                        
Research and development expense 915,457 511,433 2,661,551 1,326,197 20,111,002     107,740   57,000                                
Period from the end of proof of principle work on certain fields within which the exclusive option is exercisable                     15 days 15 days                            
Period to negotiate a license agreement if the exclusive option is exercised                     60 days 60 days                            
Period during which the license agreement must first be offered to PerkinElmer                     1 year                              
Compensation per year                             200,000               220,000   350,000  
Receipt of milestone payments                   90,000                                
Period of termination of agreement, after completion of the Research Plan                         30 days                          
Period of termination of agreement, on its anniversary unless extended by mutual written agreement                         1 year                          
Bonus as percentage of base salary                               50.00%                    
Award granted (in shares)             710,427                   200,000             60,000   200,000
Exercise price of award granted (in dollars per share)             $ 6.69                   $ 7.04             $ 6.00   $ 6.00
Vesting period of options                                 4 years             4 years   4 years
Period of base compensation which would be received as severance payment                             6 months                      
Aggregate initial offering price                                     150,000,000     30,000,000        
Commission as percentage of gross proceeds                                       3.00%            
Gross proceeds from sale of shares                                   $ 15,000,000     $ 4,200,000          
Number of shares sold 18,891,949   18,891,949   18,891,949 15,478,177                       2,142,857     488,476