Condensed Consolidated Statements of Operations and Comprehensive Loss (USD $)	3 Months Ended		6 Months Ended		167 Months Ended
	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013	Jun. 30, 2012	Jun. 30, 2013
Condensed Consolidated Statements of Operations and Comprehensive Loss
Royalty income	$ 49,000	$ 41,500	$ 168,123	$ 75,653	$ 1,093,597
License fees					1,383,175
Milestone fees					150,000
Total revenues	49,000	41,500	168,123	75,653	2,626,772
Costs and expenses:
Research and development	943,849	477,151	1,746,094	814,558	19,195,545
Purchased in process research and development					2,666,869
General and administrative	1,479,263	809,868	3,185,980	1,636,830	29,106,096
Total operating expenses	2,423,112	1,287,019	4,932,074	2,451,388	50,968,510
Loss from operations	(2,374,112)	(1,245,519)	(4,763,951)	(2,375,735)	(48,341,738)
Interest income					266,883
Interest expense	(668)		(668)		(1,326,040)
Gain on sale of equipment					4,000
Amortization of deferred debt costs and original issue discount					(2,346,330)
Change in fair value of derivative instruments-warrants	(2,895,310)	(2,180,891)	(1,616,168)	(2,213,315)	(7,110,967)
Gain on extinguishment of debt					623,383
Liquidated damages and other forbearance agreement settlement costs					(1,758,111)
Net loss and comprehensive loss	(5,270,090)	(3,426,410)	(6,380,787)	(4,589,050)	(59,988,920)
Preferred stock dividend	(9,385)	(9,560)	(15,270)	(19,120)	(361,428)
Series A Convertible Preferred stock conversion rate change accreted as a dividend					(455,385)
Cumulative effect of early adopting ASC Topic 815-40					(792,956)
Net loss and comprehensive loss available to common stockholders	$ (5,279,475)	$ (3,435,970)	$ (6,396,057)	$ (4,608,170)	$ (61,598,689)
Net loss per common share-basic and diluted (in dollars per share)	$ (0.34)	$ (0.28)	$ (0.41)	$ (0.40)
Weighted average shares outstanding- basic and diluted (in shares)	15,583,957	12,086,528	15,547,352	11,544,112