X0306 4/A 2018-01-02 2018-01-04 0 0001213037 Trovagene, Inc. TROV 0001237522 WELCH WILLIAM J C/O TROVAGENE, INC. 11055 FLINTKOTE SAN DIEGO CA 92121 1 1 0 0 Chief Executive Officer Common Stock 2018-01-02 4 M 0 50000 0.00 A 800142 D Common Stock 2018-01-02 4 F 0 25487 0.00 D 774655 D Restricted Stock Units 2018-01-02 4 M 0 50000 0.00 D Common Stock 50000 280000 D Represents the conversion upon vesting of restricted stock units into common stock (the "Converted Common Stock"). On January 2, 2017, the reporting person was granted 200,000 restricted stock units, 50,000 of which vested on January 2, 2018. Such restricted stock units were previously reported in Table II on a Form 4 filed with the Securities and Exchange Commission on January 4, 2017. The reporting person is reporting the withholding by Trovagene, Inc. of 25,487 shares of common stock to satisfy the reporting person's tax withholding obligations in connection with the delivery of the Converted Common Stock to the reporting person on January 2, 2018. Each restricted stock unit is the economic equivalent of one share of Trovagene, Inc. common stock. On January 2, 2017, the reporting person was granted 200,000 restricted stock units, 50,000 of which vested on January 2, 2018. The common stock into which such vested restricted stock units converted on January 2, 2018 is reported in Table I on this Form 4. /s/ William Welch 2018-01-04