X0202 3 2007-12-12 0 0001171662 TRIPLE-S MANAGEMENT CORP GTS 0001280190 ACCIPITER CAPITAL MANAGEMENT, LLC 399 PARK AVENUE, 38TH FLOOR NEW YORK NY 10022 0 0 1 0 0001351187 ACCIPITER LIFE SCIENCES FUND II L P 399 PARK AVE 37TH FL NEW YORK NY 10022 0 0 1 0 0001351046 Accipiter Life Sciences Fund II Offshore Ltd 399 PARK AVE 38TH FLOOR NEW YORK NY 10022 0 0 1 0 0001351186 ACCIPITER LIFE SCIENCES FUND II QP L P 399 PARK AVE 37TH FL NEW YORK NY 10022 0 0 1 0 0001211729 ACCIPITER LIFE SCIENCES FUND LP 0 0 1 0 0001214706 ACCIPITER LIFE SCIENCES FUND OFFSHORE LTD 0 0 1 0 0001351609 Candens Capital LLC C/O ACCIPITER CAPITAL MANAGEMENT, LLC 399 PARK AVENUE, 38TH FLOOR NEW YORK NY 10022 0 0 1 0 0001322420 HOFFMAN GABE C/O ACCIPITER CAPITAL MANAGEMENT, LLC 399 PARK AVENUE, 37TH FLOOR NEW YORK NY 10022 0 0 1 0 Class B Common Stock, par value $1.00 per share 463454 I By ALSF (Offshore), Ltd. Class B Common Stock, par value $1.00 per share 914062 I By ALSF II (Offshore), Ltd. Class B Common Stock, par value $1.00 per share 529079 I By ALSF II (QP), LP Class B Common Stock, par value $1.00 per share 462589 I By ALSF II, LP Class B Common Stock, par value $1.00 per share 462741 I By ALSF, LP Includes (i) 447,567 shares of Series B Common Stock purchased from the underwriters on December 12, 2007, the closing date of the Issuer's Initial Public Offering (the Closing) and (ii) 15,887 shares of Series B Common Stock purchased in the open market prior to the Closing. Held by Accipiter Life Sciences Fund (Offshore), Ltd. Accipiter Capital Management, LLC, the investment manager of Accipiter Life Sciences Fund (Offshore), Ltd. and Gabe Hoffman, the managing member of Accipiter Capital Management, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein. Includes (i) 890,042 shares of Series B Common Stock purchased from the underwriters at the Closing and (ii) 24,020 shares of Series B Common Stock purchased in the open market prior to the Closing. Held by Accipiter Life Sciences Fund II (Offshore), Ltd. Accipiter Capital Management, LLC, the investment manager of Accipiter Life Sciences Fund II (Offshore), Ltd. and Gabe Hoffman, the managing member of Accipiter Capital Management, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein. Includes (i) 515,085 shares of Series B Common Stock purchased from the underwriters at the Closing and (ii) 13,994 shares of Series B Common Stock purchased in the open market prior to the Closing. Held by Accipiter Life Sciences Fund II (QP), LP. Candens Capital, LLC, the general partner of Accipiter Life Sciences Fund II (QP), LP, and Gabe Hoffman, the managing member of Candens Capital, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein. Includes (i) 450,427 shares of Series B Common Stock purchased from the underwriters at the Closing and (ii) 12,162 shares of Series B Common Stock purchased in the open market prior to the Closing. Held by Accipiter Life Sciences Fund II, LP. Candens Capital, LLC, the general partner of Accipiter Life Sciences Fund II, LP and Gabe Hoffman, the managing member of Candens Capital, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein. Includes (i) 446,879 shares of Series B Common Stock purchased from the underwriters at the Closing and (ii) 15,862 shares of Series B Common Stock purchased in the open market prior to the Closing. Held by Accipiter Life Sciences Fund, LP. Candens Capital, LLC, the general partner of Accipiter Life Sciences Fund, LP and Gabe Hoffman, the managing member of Candens Capital, LLC, disclaim beneficial ownership of these securities except to the extent of their pecuniary interest therein. By: Accipiter Capital Management, LLC; By: /s/ Gabe Hoffman, Managing Member 2007-12-21 By: Candens Capital, LLC, its General Partner; By: s/ Gabe Hoffman, Managing Member 2007-12-21 By: Accipiter Capital Management, LLC, its Investment Manager; By: /s/ Gabe Hoffman, Managing Member 2007-12-21 By: Candens Capital, LLC, its General Partner; By: s/ Gabe Hoffman, Managing Member 2007-12-21 By: Candens Capital, LLC, its General Partner; By: s/ Gabe Hoffman, Managing Member 2007-12-21 By: Accipiter Capital Management, LLC, its Investment Manager; By: /s/ Gabe Hoffman, Managing Member 2007-12-21 /s/ Candens Capital LLC, 2007-12-21 /s/ Hoffman, Gabe 2007-12-21