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Significant Accounting Policies - Revenue recognition (Details) - USD ($) $ in Thousands	1 Months Ended		6 Months Ended	12 Months Ended
	Jan. 31, 2021	Aug. 31, 2020	Jun. 30, 2022	Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percentage of royalties		5.00%	5.00%
Revenues				$ 200
Liquidity discount (as a percent)			20.00%
1st Year Anniversary of Effective Date
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			$ 100
Liquidity discount (as a percent)			30.00%
2nd Year Anniversary of Effective Date
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			$ 100
Liquidity discount (as a percent)			40.00%
1st Patient in Dose Confirmation Study
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			$ 100
NDA Submission
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			300
1st FDA Approval in US
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			5,000
2nd FDA Approval in US
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			3,000
1st Regulatory Approval Outside US
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			2,000
2nd Regulatory Approval Outside US
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			2,000
Restricted shares \| 1st Patient in Dose Confirmation Study
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			5
Restricted shares \| NDA Submission
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payment			$ 15
Processa Pharmaceuticals, Inc
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Minimum proceeds from public offering		$ 15,000
Shares to be issued under agreement		825,000	46,000
Processa Pharmaceuticals, Inc \| Restricted shares
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Upfront payment	$ 5
Processa Pharmaceuticals, Inc \| License agreement \| Restricted shares
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Shares to be issued under agreement	41
Lockup period			1 year
Adjusted liquidity discount (as a percent)			0.00%
Processa Pharmaceuticals, Inc \| License agreement \| Restricted shares \| 1st Year Anniversary of Effective Date
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Adjusted liquidity discount (as a percent)			0.00%
Processa Pharmaceuticals, Inc \| License agreement \| Restricted shares \| 2nd Year Anniversary of Effective Date
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Adjusted liquidity discount (as a percent)			20.00%