X0203 3 2010-08-02 0 0000090185 SIGMA ALDRICH CORP SIAL 0001210653 PORWOLL JOE 1001 WEST SAINT PAUL AVE MILWAUKEE WI 53233 0 0 0 1 VP-Supply Chain-Global Common Stock, $1 Par Value 10240 D ISO Stock Option, Right to Buy 25.315 2003-05-07 2012-05-07 Common Stock, $1 Par Value 4100 D ISO Stock Option, Right to Buy 25.86 2004-05-06 2013-05-06 Common Stock, $1 Par Value 7600 D NQ Stock Option, Right to Buy 25.86 2004-05-06 2013-05-06 Common Stock, $1 Par Value 7400 D ISO Stock Option, Right to Buy 28.66 2005-05-04 2014-05-04 Common Stock, $1 Par Value 3400 D NQ Stock Option, Right to Buy 28.66 2005-05-04 2014-05-04 Common Stock, $1 Par Value 11600 D ISO Stock Option, Right to Buy 28.825 2006-07-08 2015-07-08 Common Stock, $1 Par Value 2500 D NQ Stock Option, Right to Buy 28.825 2006-07-08 2015-07-08 Common Stock, $1 Par Value 5000 D ISO Stock Option, Right to Buy 34.03 2007-05-01 2016-05-01 Common Stock, $1 Par Value 2500 D NQ Stock Option, Right to Buy 34.03 2007-05-01 2016-05-01 Common Stock, $1 Par Value 5000 D ISO Stock Option, Right to Buy 41.62 2008-02-16 2017-02-16 Common Stock, $1 Par Value 3400 D NQ Stock Option, Right to Buy 41.62 2008-02-16 2017-02-16 Common Stock, $1 Par Value 4100 D NQ Stock Option, Right to Buy 52.76 2009-02-15 2018-02-15 Common Stock, $1 Par Value 4050 D ISO Stock Option, Right to Buy 52.76 2009-02-15 2018-02-15 Common Stock, $1 Par Value 1850 D ISO Stock Option, Right to Buy 37.56 2010-02-17 2019-02-17 Common Stock, $1 Par Value 2032 D NQ Stock Option, Right to Buy 37.56 2010-02-17 2019-02-17 Common Stock, $1 Par Value 3868 D ISO Stock Option, Right to Buy 48.61 2011-02-16 2020-02-16 Common Stock, $1 Par Value 2204 D NQ Stock Option, Right to Buy 48.61 2011-02-16 2020-02-16 Common Stock, $1 Par Value 2796 D Carrie Fields, Attorney in Fact 2010-08-04