X0303 4 2010-01-23 0001116463 ORASURE TECHNOLOGIES INC OSUR 0001209784 KUNA MARK L 220 EAST FIRST STREET BETHLEHEM PA 18015 0 1 0 0 Snr. VP & Controller Common Stock 2010-01-23 2010-01-25 4 F 0 2192 5.19 D 75103 D Common Stock 2010-01-25 4 A 0 17870 A 92973 D NonQual. Stock Options 5.19 2010-01-25 4 A 0 30350 A 2020-01-25 Common Stock 30350 30350 D Withholding of shares to pay the tax liability associated with vesting of restricted shares. Grant of restricted shares under the OraSure Technologies, Inc. 2000 Stock Award Plan, with one-third of the grant vesting on January 25, 2011, January 25, 2012, and January 25, 2013. Vesting shall cease upon voluntary termination of employment. Grant of nonqualified stock options, vesting and exercisable over a four year period, with one-fourth of the options vesting on the first anniversary date of the grant and the remainder vesting ratably on a monthly basis, over the remaining 36 months. Vesting shall cease upon voluntary termination of employment. Mark L. Kuna 2010-01-26