X0306 4 2018-02-28 0 0001624899 STERIS plc STE 0001209524 KOSECOFF JACQUELINE B C/O RUTHERFORD HOUSE, STEPHENSONS WAY CHADDESDEN DERBY X0 DE21 6LY UNITED KINGDOM 1 0 0 0 Ordinary Shares, 10 pence par value 2018-02-28 4 M 0 2744 34.17 A 2744 D Ordinary Shares, 10 pence par value 2018-02-28 4 S 0 2744 91.94 D 0 D Ordinary Shares,10 pence par value 41570 I See Footnote Below Director Stock Option (right to buy) 34.17 2018-02-28 4 M 0 2744 0.00 D 2018-07-31 Ordinary Shares 2744 0 D Price reflects a weighted average sale price for multiple transactions ranging from $91.80 to $92.15 per share, inclusive. The Reporting Person undertakes to provide, upon request by the SEC Staff, the Issuer or a security holder of the Issuer, full information regarding the number of shares sold at each separate price These Ordinary Shares are held in a revocable family trust of the Reporting Person and the Reporting Person's spouse, as Co-Trustees. 1,230 shares that had been directly held were transferred to the trust on December 1, 2017. This option to purchase 2,744 STERIS plc ordinary shares, which is fully vested, was received in conjunction with the "Combination" of STERIS Corporation and Synergy Health, Ltd. in exchange for an option to purchase 2,744 STERIS Corporation common shares for $34.17 per share, subject to the same terms and conditions as the original STERIS Corporation stock option. /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney 2018-03-01