Note 10 - Stockholders' Equity (Tables)

3 Months Ended

Mar. 31, 2014

Disclosure of Compensation Related Costs, Share-based Payments [Abstract]

Schedule of Other Share-based Compensation, Activity [Table Text Block]

	Shares			Range of Exercise Price				Weighted Average Exercise Price
Options outstanding at December 31, 2011		—		$		—		$	—
Granted		3,890,534			0.03	—	2.00		0.33
Forfeited		(115,000	)		0.44	—	0.61		0.57
Options outstanding at December 31, 2012		3,775,534			0.03	—	2.00		0.32
Granted		790,000			0.61	—	1.80		1.15
Forfeited		(528,958	)		0.03	—	0.61		0.33
Transferred to Immune 2013 Plan		(4,036,576	)	$	0.03	—	2.00		0.37
Options outstanding at December 31, 2013 and March 31, 2014		—						$	—

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

Title	Grant date	No. of options	Exercise price			Share price at grant date			Vesting terms (years)			Assumptions used in Black-Scholes option pricing model
Management, Directors and Employees	February 2014	1,075,000		$2.38			$2.38		Over 1.0	-	3.0	Volatility		89%
												Risk free interest rate		2.82%
												Expected term, in years		10.00
												Dividend yield		0.00%
Consultants	February-March 2014	155,000	$2.38	-	$4.00	$2.38	-	$4.00		Over 1.0		Volatility		89%
												Risk free interest rate	2.82%	-	3.01%
												Remaining expected term, in years		10.00
												Dividend yield		0.00%

Schedule of Share-based Compensation, Restricted Stock Units Award Activity [Table Text Block]

Title	Grant date	No. of stock awards	Share price at grant date			Vesting terms (years)
Consultants	January-March 2014	715,955	$1.70	-	$4.82	Over 0	-	3

Schedule of Share-based Compensation, Activity [Table Text Block]

	Stock awards					Options
	No. of stock awards			Weighted average grant date fair value		No. of options			Weighted average exercise price		Exercise price range			Weighted average grant date fair value		Aggregate Intrinsic Value
Outstanding at January 1, 2014		—			—		3,192,849		$	3.81	$0.04	—	$4,153.00	$	1.67	$	12,042
Granted		715,955		$	2.33		1,230,000		$	2.53	$2.38	—	$4.67	$	2.15	$	2,818
Exercised		(415,955	)	$	2.64		—			—		—			—		—
Forfeited		—			—		—			—		—			—		—
Expired					—		(276	)	$	5,648		$5,648.40			—	$	—
Outstanding at March 31, 2014		300,000		$	2.25		4,422,573		$	3.10	$0.04	-	$4,153.00	$	1.81	$	14,860
Exercisable at March 31, 2014		—			—		2,917,809		$	3.51	$0.04	-	$5,648.40	$	1.64	$	14,507

Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]

	Number of Warrants			Weighted Average Exercise Price		Exercise price range
Warrants outstanding at January 1, 2014		2,005,684		$	16.23	$1.10	-	$124.20
Issued in connection with March 2014 financing (1)		3,361,904		$	4.68	$4.25	-	$5.10
Issuance to lead investors (2)		134,004		$	5.04		$5.04
Expired		(11,574	)	$	135.00		$135.00
Warrants outstanding at March 31, 2014		5,490,018		$	8.84	$1.10	-	$124.20