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Note 11 - Stock Option Plans (Tables)

12 Months Ended

Dec. 31, 2013

Note 11 - Stock Option Plans (Tables) [Line Items]

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

		Options				Weighted Average Exercise Price				Weighted Average Remaining Contractual Term (years)				Aggregate Intrinsic Value (000’s)
Options outstanding - 2005 Plan at August 25, 2013			56,920			$	161.46				5.34			$	—
Granted - Assumed options in merger - 2013 Plan			2,495,951				0.60				8.62				4,295
Granted options - 2005 Plan			640,000				2.47				9.82				4,331
Exercised			—				—
Forfeited			—				—
Expired – 2005 Plan			(22	)			4,153.20
Options outstanding - 2005 and 2013 Plans			3,192,849			$	3.81				8.80			$	4,295

Vested or expected to vest at December 31, 2013 - 2005 and 2013 Plans			3,158,470			$	3.86				8.79			$	4,283

Options exercisable at December 31, 2013 - 2005 and 2013 Plans			2,852,010			$	4.05				8.72			$	4,174

Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

	Years Ended December 31,
	2013				2012
Expected volatility	92%	–	95%			92%
Risk free interest rate	0.7%	–	3.0%		0.9%	–	2.0%
Dividend yield		–				–
Expected life (years)	5	–	10		5	–	10
Exercise price	$0.61	–	$2.50		$0.03	–	$2.00

Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]

		Warrants				Weighted Average Exercise Price
Warrants outstanding at August 25, 2013			526,642			$	55.66
Issued			101,531				3.50
Assumed warrants			1,377,511				2.09
Exercised			—				—
Expired			—				—
Warrants outstanding at December 31, 2013			2,005,684			$	16.23

Immune Ltd Plan [Member]

Note 11 - Stock Option Plans (Tables) [Line Items]

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

		Shares				Range of Exercise Price						Weighted Average Exercise Price
Options outstanding at July11, 2010			—			$		—				$	—
Granted			—					—					—
Options outstanding at December 31, 2010			—					—					—
Granted			—					—					—
Options outstanding at December 31, 2011			—					—					—
Granted			3,890,534				0.03	—	2.00				0.33
Forfeited			(115,000	)			0.44	—	0.61				0.57
Options outstanding at December 31, 2012			3,775,534				0.03	—	2.00				0.32
Granted			790,000				0.61	—	1.80				1.15
Forfeited			(528,958	)			0.03	—	0.61				0.33
Transferred to Immune Inc. 2013 Plan			(4,036,576	)			0.03	—	2.00				0.37

Options outstanding at December 31, 2013			—			$		—				$	—

Tabular disclosure of warrants or rights issued. Warrants and rights outstanding are derivative securities that give the holder the right to purchase securities (usually equity) from the issuer at a specific price within a certain time frame. Warrants are often included in a new debt issue to entice investors by a higher return potential. The main difference between warrants and call options is that warrants are issued and guaranteed by the company, whereas options are exchange instruments and are not issued by the company. Also, the lifetime of a warrant is often measured in years, while the lifetime of a typical option is measured in months. Disclose the title of issue of securities called for by warrants and rights outstanding, the aggregate amount of securities called for by warrants and rights outstanding, the date from which the warrants or rights are exercisable, and the price at which the warrant or right is exercisable.

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