Note 11 - Stock Option Plans (Tables)

9 Months Ended

Sep. 30, 2013

Note 11 - Stock Option Plans (Tables) [Line Items]

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

	Options		Weighted Average Exercise Price		Weighted Average Remaining Contractual Term (years)		Aggregate Intrinsic Value (000’s)
Options outstanding - 2005 Plan		56,920	$	161.24		6.45	$	—
Granted Assumed options in merger - 2013 Plan		2,495,951		0.37		8.86		4,331
Exercised		—		—
Granted		—		—
Options outstanding - 2005 and 2013 Plans		2,552,871	$	3.96		8.79	$	4,331
Vested or expected to vest at September 30, 2013 - 2005 and 2013 Plans		2,474,082	$	4.29		8.79	$	4,234
Options exercisable at September 30, 2013 - 2005 and 2013 Plans		2,277,256	$	4.52		8.78	$	3,892

Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]

	Three Months Ended September 30,				Nine Months Ended September 30,
	2013		2012		2013		2012
	(in $000s)				(in $000s)
General and administrative	$	730	$	1,546	$	2,081	$	2,557
Research and development		14		256		122		428
Stock-based compensation expense before income taxes		744		1,802		2,203		2,985
Benefit for income taxes (1)		—		—		—		—
Net compensation expense	$	744	$	1,802	$	2,203	$	2,985

Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]

	Nine Months Ended September 30,
	2013			2012
Expected volatility	91.9			91.9	–	110%
Risk free interest rate	0.74%	–	1.89%	0.89%	–	2.01%
Dividend yield	–				–
Expected life (years)	5	–	10	5	–	10
Exercise price	$0.61	–	$1.80	$0.03	–	$2.00

Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]

	Warrants		Weighted Average Exercise Price
Warrants outstanding at august 25, 2013		526,642	$	55.66
Issued		101,531		3.50
Assumed warrants		1,377,511		2.09
Exercised		—		—
Expired		—		—
Warrants outstanding at September 30, 2013		2,005,684	$	16.29

Immune Ltd Plan [Member]

Note 11 - Stock Option Plans (Tables) [Line Items]

Schedule of Share-based Compensation, Stock Options, Activity [Table Text Block]

	Shares			Range of Exercise Price				Weighted Average Exercise Price
Options outstanding at July11, 2010		—		$		—		$	—
Granted		—				—			—
Options outstanding at December31, 2010		—				—			—
Granted		—				—			—
Options outstanding at December31, 2011		—				—			—
Granted		3,890,534			0.03	—	2.00		0.33
Forfeited		(115,000	)		0.44	—	0.61		0.57
Options outstanding at December31, 2012		3,775,534			0.03	—	2.00		0.32
Granted		790,000			0.61	—	1.80		1.15
Forfeited		(528,958	)		0.03	—	0.61		0.33
Transferred to Immune Inc. 2013 Plan		(4,036,576	)		0.03	—	2.00		0.37
Options outstanding at September 30, 2013		—		$		—		$	—