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Notes and Loan Payable (Details Textual) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
May 14, 2018
Dec. 15, 2017
Jul. 26, 2018
Jun. 15, 2018
May 31, 2018
May 28, 2018
May 18, 2018
May 09, 2018
Dec. 31, 2017
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Jun. 15, 2017
Dec. 31, 2016
Feb. 28, 2014
Mar. 31, 2012
Notes and Loans Payable [Line Items]                                  
Loans Payable                   $ 510,000   $ 510,000          
Interest Expense                   281,000 $ 2,142,000 346,000 $ 3,197,000        
Loss Contingency, Damages Sought, Value               $ 2,800,000                  
Gain (Loss) on Extinguishment of Debt           $ 181,000       181,000 0 181,000 0        
Proceeds From Convertible Notes Two                       2,007,000 0        
Warrants Not Settleable in Cash, Fair Value Disclosure $ 91,000                                
Amortization of Debt Issuance Costs and Discounts         $ 865,000                        
Number of Warrant Issued 474,667                                
Class of Warrant or Right, Exercise Price of Warrants or Rights $ 0.47                                
Liquidated Damages                   $ 1,112,000 0 1,112,000 0        
Proceeds from Notes Payable                       $ 3,000,000          
Minimum Bid Price                   $ 1.00   $ 1.00          
Mandatory Default Amount Percentage on Principal                   40.00%   40.00%          
Deemed Dividend                   $ (5,599,000) $ 0 $ (5,599,000) 0        
Series E Warrants [Member]                                  
Notes and Loans Payable [Line Items]                                  
Warrant, Exercise Price, Decrease             $ 0.30                    
Deemed Dividend                   424,000   424,000          
Series E Preferred Stock [Member]                                  
Notes and Loans Payable [Line Items]                                  
Preferred Stock, Convertible, Conversion Price, Decrease             $ 0.30                    
Deemed Dividend                   5,175,000   $ 5,175,000          
Meda Pharma SARL [Member]                                  
Notes and Loans Payable [Line Items]                                  
Fixed Consideration Payable in Installments Over Three Year Period description                       In conjunction with the Asset Purchase Agreement with Meda described in Note 6, we agreed to pay a fixed consideration of $5.0 million, payable in installments over a three-year period as follows: (i) $1.5 million on the earlier of: (1) the successful transfer to us of all of the marketing authorizations for the product or (2) the date which is six months after the Completion Date (as defined in the Asset Purchase Agreement); (ii) $1.5 million on the first anniversary of the Completion Date; (iii) $1.0 million on the second anniversary of the Completion Date; and (iv) $1.0 million on the third anniversary of the Completion Date.          
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Long-term Debt                   3,600,000   $ 3,600,000          
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Noncurrent Liabilities, Long-term Debt                   900,000   900,000          
Payments for Asset Purchase Agreement Amount   $ 1,500,000   $ 1,500,000                          
Debt Instrument, Interest Rate, Stated Percentage                           15.00%      
Mablife Notes Payable [Member]                                  
Notes and Loans Payable [Line Items]                                  
Notes Payable                             $ 100,000    
Interest Expense                       0 $ 0        
Loss Contingency, Damages Sought, Value                 $ 205,000                
Asset Acquisition Payable [Member]                                  
Notes and Loans Payable [Line Items]                                  
Interest Expense                       65,000          
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Long-term Debt                   3,000,000   3,000,000          
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Noncurrent Liabilities, Long-term Debt                   1,400,000   1,400,000          
Debt Instrument, Unamortized Discount                   649,000   649,000          
Convertible Notes Two [Member]                                  
Notes and Loans Payable [Line Items]                                  
Debt Instrument, Face Amount $ 2,781,000                                
Debt Instrument, Unamortized Discount $ 556,000                                
Proceeds From Convertible Notes Two           $ 2,007,000                      
Debt Instrument Unamortized Discount Percentage 20.00%                                
Debt InstrumentPlacement Agent Fee Percentage         8.00%                        
Placement Agent Fee         $ 178,000                        
Other Placement Agent Fee         $ 40,000                        
Debt Instrument, Convertible, Conversion Price $ 0.375                                
Debt Conversion Converted Instrument Maximum Shares to be Issued 6,397,456                                
Debt Instrument, Maturity Date, Description The May 2018 Convertible Notes are due and payable upon the earlier of (a) November 18, 2018 and (b) the closing by of one or more subsequent financings with gross proceeds equal to at least $3,000,000 in the aggregate. The holders of the May 2018 Convertible Notes have the option to extend the maturity date of the notes through February 18, 2019. The May 2018 Convertible Notes represent senior indebtedness of the Company.                                
Interest Expense, Debt                   $ 216,000   $ 216,000          
Debt Instrument, Interest Rate, Stated Percentage         1.50%         19.99%   19.99%          
Liquidated Damages                   $ 1,112,000   $ 1,112,000          
Debt Instrument Debt Default Percentage         140.00%                        
Mablife [Member]                                  
Notes and Loans Payable [Line Items]                                  
Loans Payable                                 $ 600,000
Royalty Rate Percent of Net Sales                                 0.60%
Purchase Obligation, Due in Fourth Year                               $ 25,000  
Purchase Obligation, Due in Fifth Year                               35,000  
Mablife [Member] | Secondary Patent Rights [Member]                                  
Notes and Loans Payable [Line Items]                                  
Purchase Obligation, Due in Second Year                               15,000  
Purchase Obligation, Due in Third Year                               25,000  
Purchase Obligation                               $ 150,000  
Subsequent Event [Member] | Series E Warrants [Member]                                  
Notes and Loans Payable [Line Items]                                  
Warrant, Exercise Price, Decrease     $ 0.20                            
Subsequent Event [Member] | Series E Preferred Stock [Member]                                  
Notes and Loans Payable [Line Items]                                  
Preferred Stock, Convertible, Conversion Price, Decrease     $ 0.20