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Loss Per Share (Tables)
6 Months Ended
Jun. 30, 2018
Earnings Per Share [Abstract]  
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Such excluded shares are summarized as follows:
 
 
 
Three month period
 
 
Six month period
 
 
 
ended June 30,
 
 
ended June 30,
 
 
 
2018
 
 
2017
 
 
2018
 
 
2017
 
Common stock options
 
 
575,597
 
 
 
490,541
 
 
 
575,597
 
 
 
490,541
 
Shares issuable upon conversion of Series E Preferred Stock (not including dividends)
 
 
16,171,200
 
 
 
-
 
 
 
16,171,200
 
 
 
-
 
Shares potentially issuable upon conversion of May 2018 convertible notes (assuming $0.375 price)
 
 
7,416,667
 
 
 
-
 
 
 
7,416,667
 
 
 
-
 
Shares potentially issuable upon conversion of April 2017 convertible notes (assuming $1.00 floor price)
 
 
-
 
 
 
305,000
 
 
 
-
 
 
 
305,000
 
Shares potentially issuable upon conversion of May 2017 convertible notes (assuming $1.00 floor price)
 
 
-
 
 
 
2,344,354
 
 
 
-
 
 
 
2,344,354
 
Warrants
 
 
19,170,344
 
 
 
715,413
 
 
 
19,170,344
 
 
 
715,413
 
Total shares excluded from calculation
 
 
43,333,808
 
 
 
3,855,308
 
 
 
43,333,808
 
 
 
3,855,308