Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2015	Sep. 30, 2014
Cash flows from operating activities:
Net loss	$ (10,592)	$ (16,460)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	242	250
Share-based compensation	2,635	5,457
Common shares issued for services	280	0
Derivative liability expense	141	478
Warrant amendment expense	0	3,145
Amortization of debt discount	71	33
Changes in operating assets and liabilities:
Increase in other current assets	(90)	(45)
Increase in security deposits	(177)	0
(Decrease) increase in accounts payable	7	(2,495)
Decrease in due to related parties	(30)	(469)
Decrease in accrued expenses	(2,340)	(378)
Decrease in long term grants payable	(4)	(27)
Net cash used in operating activities	(9,857)	(10,511)
Cash flows from investing activities:
(Increase) decrease in restricted cash	(49)	139
Purchase of property and equipment	(31)	(24)
Net cash (used in) provided by investing activities	(80)	115
Cash flows from financing activities:
Proceeds from Series D Preferred issuance	12,000	0
Payment of fees in connection with Series D Financing	(764)	0
Proceeds from issuance of shares, net of issuance costs	0	2,384
Proceeds received from exercise of options	143	251
Proceeds from July 2015 debt financing	4,500	0
Payment of fees in connection with July 2015 debt financing	(556)	0
Proceeds received from March 2014 financing	0	10,171
Proceeds received from deposits for future financing	0	(500)
Repayment of loans	(3,197)	(1,025)
Net cash provided by financing activities	12,126	11,281
Increase in cash and cash equivalents	2,189	885
Cash and cash equivalents at beginning of period	6,767	49
Cash and cash equivalents at end of period	8,956	934
Supplemental disclosure of cash flow information:
Cash paid for interest	271	333
Supplemental disclosure of non-cash financing activities:
Accrued dividends on Series C Preferred Stock	121	314
Dividends settled in common stock	340	0
Conversion of Series C Preferred Stock into common stock	818	0
Reclassification of March 2014 warrants from liability to equity	0	10,202
Reclassification of Series C Preferred Stock due to amendment	0	1,206
Services expensed and accrued in 2014 and settled in common stock in 2015	258	0
Stock issued for future financing services	100	0
Offset of debt in March 2014 financing	0	329
Amendment of Series C Preferred Stock	0	1,887
Warrants issued to Series D Preferred Stock placement agents	758	0
Warrants issued to July 2015 debt financings placement agent	731	0
Series D Preferred Stock Original Issue Discount	630
Intangible acquired with note payable	0	111
Deemed dividend	$ (5,363)	$ (616)