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Condensed Consolidated Statements of Cash Flows (Unaudited) (USD $)
In Thousands, unless otherwise specified
9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Cash flows from operating activities:    
Net loss $ (1,701) $ (12,205)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 49 96
Foreign exchange (gain) loss 57 (38)
Stock-based compensation expense 394 753
Excess inventory expense   361
Warrant amendment expense 936  
Amortization and write-off of deferred financing costs and discount on loans 408 762
Changes in operating assets and liabilities:    
Increase in accounts receivable (226)  
Decrease (increase) in inventory 354 (1)
Decrease (increase) in prepaid expenses and other current assets 157 (39)
Decrease in accounts payable (252) (192)
Increase in accrued research contract costs 656 768
Increase in other accrued liabilities 213 522
Recognition of deferred revenue (5,066) (668)
Decrease in other liabilities (168) (204)
Net cash used in operating activities (4,189) (10,085)
Cash flows from investing activities:    
Establishment of restricted cash in connection with senior secured term loan   (118)
Release of restricted cash in connection with conversion of 7.5556% convertible subordinated notes   118
Proceeds from sale of property and equipment   5
Purchases of property and equipment   (12)
Net cash (used in) provided by investing activities (1,107) 111
Cash flows from financing activities:    
Proceeds from exercise of warrants 1,541  
Proceeds from issuance of preferred stock and warrants, net of issuance costs 2,833  
Proceeds from issuance of common stock and warrants, net of issuance costs   10,872
Proceeds from loans and warrants   8,600
Deferred financing costs   (273)
Repayment of loans (4,314) (1,043)
Net cash provided by financing activities 60 18,156
Effect of exchange rate changes on cash and cash equivalents (11) (1)
Net (decrease) increase in cash and cash equivalents (5,247) 8,181
Cash and cash equivalents at beginning of year 6,378 2,435
Cash and cash equivalents at end of period 1,131 10,616
Supplemental disclosure of cash flow information:    
Cash paid for interest 614 394
Cash paid for income taxes 2 4
Conversion of preferred stock to common stock 1  
Beneficial conversion feature in connection with issuance of preferred stock 3,550  
Unpaid costs associated with issuance of preferred stock and warrants 74  
Unpaid financing costs 301 310
Senior Secured Term Loan [Member]
   
Cash flows from investing activities:    
Establishment of restricted cash in connection with senior secured term loan (1,107)  
Release of restricted cash in connection with conversion of 7.5556% convertible subordinated notes $ 1,107