Subsequent Event - Additional Information (Details) - USD ($)		1 Months Ended	3 Months Ended		12 Months Ended
	Jan. 21, 2020	Jan. 31, 2022	Sep. 30, 2020	Jun. 30, 2020	Dec. 31, 2021	Dec. 31, 2020
Subsequent Event [Line Items]
Common stock, shares issued					30,801,962	22,388,027
Proceeds from issuance of common stock					$ 32,848,000	$ 17,000,000
Dr. Maurice Zauderer
Subsequent Event [Line Items]
Common stock, shares issued	982,318
Proceeds from issuance of common stock	$ 4,999,999
Chief Executive Officer
Subsequent Event [Line Items]
Common stock, shares issued	98,231
Proceeds from issuance of common stock	$ 499,996
Board of Directors
Subsequent Event [Line Items]
Common stock, shares issued	39,292
Proceeds from issuance of common stock	$ 199,996
Open Market Sale Agreement
Subsequent Event [Line Items]
Aggregate number of shares issued and sell					5,937,900
Proceeds from the sale of shares			$ 12,300,000	$ 1,200,000
Common Stock | Open Market Sale Agreement
Subsequent Event [Line Items]
Aggregate number of shares issued and sell			3,815,600	317,688
Subsequent Event | January 2022 Private Placement | Dr. Maurice Zauderer
Subsequent Event [Line Items]
Common stock, shares issued		5,495,493
Proceeds from issuance of common stock		$ 6,100,000
Subsequent Event | January 2022 Private Placement | Chief Executive Officer
Subsequent Event [Line Items]
Common stock, shares issued		5,495,493
Proceeds from issuance of common stock		$ 6,100,000
Subsequent Event | January 2022 Private Placement | Board of Directors
Subsequent Event [Line Items]
Common stock, shares issued		5,495,493
Proceeds from issuance of common stock		$ 6,100,000
Subsequent Event | Common Stock | Open Market Sale Agreement
Subsequent Event [Line Items]
Aggregate number of shares issued and sell		3,115,197
Shares issued, price per share		$ 1.16
Proceeds from the sale of shares		$ 3,500,000
Subsequent Event | Common Stock | Private Placement
Subsequent Event [Line Items]
Aggregate number of shares issued and sell		8,747,744
Shares issued, price per share		$ 1.11
Proceeds from the sale of shares		$ 9,700,000
Subsequent Event | Common Stock | January 2022 Private Placement
Subsequent Event [Line Items]
Aggregate number of shares issued and sell		8,747,744
Shares issued, price per share		$ 1.11
Proceeds from the sale of shares		$ 9,700,000