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Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Details)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Expected income tax benefit at the federal statutory rate 21.00% 21.00%
State taxes, net of federal benefit 5.30% 5.10%
Research and development credit, net 5.50% 8.20%
Non-deductible items and others 0.60% (0.20%)
Change in valuation allowance (32.40%) (34.10%)
Total 0.00% 0.00%