Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2021

Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]

Summary of Stock Option Activity and Related Information

A summary of the Company’s stock option activity and related information is as follows:

	Stock Options			Weighted- Average Exercise Price		Weighted- Average Remaining Contractual Life (Years)		Aggregate Intrinsic Value (in thousands)
Balance as of January 1, 2020		579,731		$	8.04		7.0	$	120
Granted		330,845			4.45
Exercised		(3,783	)		5.11			$	3
Forfeited		(73,925	)		5.82
Balance as of December 31, 2020		832,868			6.83		6.9	$	2
Granted		346,944			2.47
Exercised		-			-			$	-
Forfeited		(25,249	)		5.62
Balance as of December 31, 2021		1,154,563		$	5.55		6.9	$	-
Exercisable as of December 31, 2021		671,042		$	7.16		5.7	$	-

Grant Date Fair Value of Employee Stock Options Estimated Using Black-Scholes Option-Pricing Model with Weighted-Average Assumptions

The grant date fair value of employee stock options was estimated using a Black-Scholes option-pricing model with the following weighted-average assumptions:

	Year Ended December 31,
	2021			2020
Expected term (in years)		6.0			6.3
Expected volatility		75	%		75	%
Risk-free interest rate		0.7	%		0.9	%
Expected dividend yield		-	%		-	%

Total Stock-Based Compensation Expense Recognized in Condensed Consolidated Statements of Operations and Comprehensive Loss

Total stock-based compensation expense recognized in the consolidated statements of operations and comprehensive loss is as follows (in thousands):

	Year Ended December 31,
	2021		2020
Research and development	$	160	$	129
General and administrative		381		603
Total stock-based compensation expense	$	541	$	732