X0306 4 2019-09-30 0 0001205922 VACCINEX, INC. VCNX 0001205922 VACCINEX, INC. C/O VACCINEX, INC. 1895 MOUNT HOPE AVENUE ROCHESTER NY 14620 1 0 0 0 Stock Option (Right to Buy) 10.00 2020-03-06 Common Stock 4500 4500 D Stock Option (Right to Buy) 14.90 2023-03-06 Common Stock 7500 7500 D Stock Option (Right to Buy) 13.60 2027-09-15 Common Stock 6396 6396 D Stock Option (Right to Buy) 5.26 2029-03-30 Common Stock 2501 2501 D Stock Option (Right to Buy) 7.78 2020-05-15 Common Stock 7718 7718 D Stock Option (Right to Buy) 7.17 2019-09-30 4 A 0 1856 0.00 A 2019-09-30 2019-09-27 Common Stock 1856 1856 D Exercisable in full as of the date of this report. Except as otherwise provided in the award notice, this option expires on May 14, 2029 or five years following retirement or cessation of services, whichever occurs first. Pursuant to the Issuer's Director Compensation Program, in a transaction exempt under Rule 16b-3, the reporting person elected to receive these options in lieu of $8,750 for retainer and meeting fees during the third quarter of 2019. The number of options was calculated in accordance with the Black-Scholes valuation model and all of such options are immediately exercisable. /s/ Scott E. Royer, Attorney-in-Fact for Gerald E. Van Strydonck 2019-10-02