X0508 4 2024-11-14 0001205922 VACCINEX, INC. VCNX 0001747753 Zauderer Maurice C/O VACCINEX, INC. 1895 MOUNT HOPE AVENUE ROCHESTER NY 14620 1 1 1 0 President and CEO 0001747866 Vaccinex (Rochester), L.L.C. 44 WOODLAND ROAD PITTSFORD NY 14534 0 0 1 0 0 Common Stock 1580 D Common Stock 1016 I By Jeremy C. Zauderer Trust Common Stock 1011 I By Jordan M. Zauderer Trust Common Stock 2024-11-14 4 A 0 46153 3.25 A 297941 I By Vaccinex (Rochester), L.L.C. Warrant (Right to Buy) 5.636 2024-09-18 2029-09-18 Common Stock 170475 170475 I By Vaccinex (Rochester), L.L.C. Stock Option (Right to Buy) 1491.0 2025-12-23 Common Stock 15 15 D Stock Option (Right to Buy) 1402.8 2025-02-24 Common Stock 135 135 D Stock Option (Right to Buy) 615.3 2031-04-02 Common Stock 66 66 D Stock Option (Right to Buy) 270.9 2032-04-01 Common Stock 133 133 D Stock Option (Right to Buy) 92.26 2028-03-30 Common Stock 266 266 D Stock Option (Right to Buy) 8.21 2034-03-21 Common Stock 1877 1877 D Dr. Zauderer exercises voting control over shares held by this trust and disclaims beneficial ownership over these shares except to the extent of his pecuniary interest therein. Dr. Zauderer is the president and a majority owner of Vaccinex (Rochester), L.L.C. and disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein. Exercisable in full as of the date of this report. This option vests one-fourth on each of the first four anniversaries of the April 2, 2021 grant date, except as otherwise provided in the award notice. This option vests one-fourth on each of the first four anniversaries of the April 1, 2022 grant date, except as otherwise provided in the award notice. This option vests one-fourth on each of the first four anniversaries of the March 31, 2023 grant date, except as otherwise provided in the award notice. This option vests one-fourth on each of the first four anniversaries of the March 21, 2024 grant date, except as otherwise provided in the award notice. /s/ Maurice Zauderer 2024-11-18 Vaccinex (Rochester) L.L.C. By: /s/ Maurice Zauderer, President 2024-11-18