X0508 4/A 2024-03-21 2024-03-22 0001205922 VACCINEX, INC. VCNX 0001747769 Smith Ernest S. C/O VACCINEX, INC. 1895 MOUNT HOPE AVENUE ROCHESTER NY 14620 0 1 0 0 SVP, Research & CSO 0 Stock Option (Right to Buy) 8.21 2024-03-21 4 A 0 1341 0 A 2034-03-21 Common Stock 1341 1341 D Due to an administrative error, the original Form 4 mistakenly listed the transaction date as March 20, 2024. The transaction actually occurred on March 21, 2024. Accordingly, the exercise price of the stock option is $8.21 per share, as opposed to the exercise price of $8.32 that was listed in the original Form 4. This option was granted under the Company's 2018 Omnibus Incentive Plan in a transaction exempt under Rule 16b-3 and, except as otherwise provided in the award notice, vests one-fourth on each of the first four anniversaries of the March 21, 2024 grant date. /s/ Maurice Zauderer, Attorney-in-Fact for Ernest S. Smith 2024-05-14