X0508 4 2024-03-20 0001205922 VACCINEX, INC. VCNX 0002015024 Sanchez Jill C/O VACCINEX, INC. 1895 MOUNT HOPE AVE. ROCHESTER NY 14620 0 1 0 0 Chief Financial Officer 0 Stock Option (Right to Buy) 1045.8 2029-01-27 Common Stock 9 9 D Stock Option (Right to Buy) 1205.4 2029-08-30 Common Stock 9 9 D Stock Option (Right to Buy) 802.2 2030-04-04 Common Stock 19 19 D Stock Option (Right to Buy) 615.3 2031-04-02 Common Stock 19 19 D Stock Option (Right to Buy) 270.9 2032-04-02 Common Stock 38 38 D Stock Option (Right to Buy) 83.9 2033-03-28 Common Stock 76 76 D Stock Option (Right to Buy) 8.32 2024-03-20 4 A 0 805 0 A 2034-03-20 Common Stock 805 805 D This option is fully exercisable as of the date of this report. This option vests one-fourth on each of the first four anniversaries of the April 3, 2020 grant date, except as otherwise provided in the award notice. This option vests one-fourth on each of the first four anniversaries of the April 2, 2021 grant date, except as otherwise provided in the award notice. This option vests one-fourth on each of the first four anniversaries of the April 1, 2022 grant date, except as otherwise provided in the award notice. This option vests one-fourth on each of the first four anniversaries of the March 31, 2023 grant date, except as otherwise provided in the award notice. This option was granted under the Company's 2018 Omnibus Incentive Plan in a transaction exempt under Rule 16b-3 and, except as otherwise provided in the award notice, vests one-fourth on each of the first four anniversaries of the March 30, 2024 grant date. /s/ Maurice Zauderer, Attorney-in-Fact for Jill Sanchez 2024-03-22