X0202 4 2005-10-20 0 0000939767 EXELIXIS INC EXEL 0001202102 SCANGOS GEORGE A C/O EXELIXIS INC. 170 HARBOR WAY, PO BOX 0511 SAN FRANCISCO CA 94083-0511 1 1 0 0 President, CEO & Director Common Stock 2005-10-20 4 S 0 200 7.46 D 1539641 D Common Stock 2005-10-20 4 S 0 200 7.43 D 1539441 D Common Stock 2005-10-20 4 S 0 100 7.48 D 1539341 D Common Stock 2005-10-20 4 S 0 100 7.42 D 1539241 D Common Stock 2005-10-20 4 S 0 200 7.39 D 1539041 D Common Stock 2005-10-20 4 S 0 100 7.38 D 1538941 D Common Stock 2005-10-20 4 S 0 100 7.34 D 1538841 D Common Stock 2005-10-20 4 S 0 100 7.31 D 1538741 D Common Stock 2005-10-20 4 S 0 100 7.32 D 1538641 D Common Stock 2005-10-20 4 S 0 100 7.37 D 1538541 D Common Stock 2005-10-20 4 S 0 100 7.38 D 1538441 D Common Stock 2005-10-20 4 S 0 100 7.31 D 1538341 D Common Stock 2005-10-20 4 S 0 200 7.26 D 1538141 D Common Stock 2005-10-20 4 S 0 100 7.20 D 1538041 D Common Stock 2005-10-20 4 S 0 100 7.23 D 1537941 D Common Stock 2005-10-20 4 S 0 100 7.17 D 1537841 D Common Stock 2005-10-20 4 S 0 100 7.19 D 1537741 D Common Stock 2005-10-20 4 S 0 200 7.25 D 1537541 D Common Stock 2005-10-20 4 S 0 200 7.445 D 1537341 D The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 7, 2005. /s/ George Scangos 2005-10-21