-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 MblFFTCHL0vgA+V8vSE426K0n9XCtEVTHgWXc/HUyk4QyE0UI4CkNxla2nJUt7sX
 GKlrZr6NfQehrcoyni7jLQ==

<SEC-DOCUMENT>0001179110-03-008838.txt : 20031016
<SEC-HEADER>0001179110-03-008838.hdr.sgml : 20031016
<ACCEPTANCE-DATETIME>20031016094301
ACCESSION NUMBER:		0001179110-03-008838
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20031016
FILED AS OF DATE:		20031016

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			YOUNG DALE L
		CENTRAL INDEX KEY:			0001202014

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-14429
		FILM NUMBER:		03942954

	BUSINESS ADDRESS:	
		STREET 1:		4700 SUPERIOR STREET
		CITY:			LINCOLN
		STATE:			NE
		ZIP:			68504
		BUSINESS PHONE:		4024640231

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ISCO INC
		CENTRAL INDEX KEY:			0000773730
		STANDARD INDUSTRIAL CLASSIFICATION:	INDUSTRIAL INSTRUMENTS FOR MEASUREMENT, DISPLAY, AND CONTROL [3823]
		IRS NUMBER:				470461807
		STATE OF INCORPORATION:			NE
		FISCAL YEAR END:			0730

	BUSINESS ADDRESS:	
		STREET 1:		4700 SUPERIOR ST
		CITY:			LINCOLN
		STATE:			NE
		ZIP:			68504
		BUSINESS PHONE:		4024640231

	MAIL ADDRESS:	
		STREET 1:		4700 SUPERIOR ST
		CITY:			LINCOLN
		STATE:			NE
		ZIP:			68504
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgar.xml
<DESCRIPTION>FORM 4 -
<TEXT>
<XML>
<ownershipDocument>
    <schemaVersion>X0201</schemaVersion>

    <documentType>4</documentType>
<periodOfReport>2003-10-16</periodOfReport>
<notSubjectToSection16>0</notSubjectToSection16>
    <issuer>
        <issuerCik>0000773730</issuerCik>
        <issuerName>ISCO INC</issuerName>
        <issuerTradingSymbol>ISKO</issuerTradingSymbol>
</issuer>
<reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001202014</rptOwnerCik>
            <rptOwnerName>YOUNG DALE L</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>P.O. 82531</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>LINCOLN</rptOwnerCity>
            <rptOwnerState>NE</rptOwnerState>
            <rptOwnerZipCode>68531</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
<isDirector>1</isDirector>
<isOfficer>0</isOfficer>
<isTenPercentOwner>0</isTenPercentOwner>
<isOther>0</isOther>
<officerTitle></officerTitle>
<otherText></otherText>
</reportingOwnerRelationship>
</reportingOwner>
<nonDerivativeTable><nonDerivativeTransaction><securityTitle><value>Common Stock</value>
</securityTitle>
<transactionDate><value>2003-10-16</value>
</transactionDate>
<transactionCoding><transactionFormType>4</transactionFormType>
<transactionCode>G</transactionCode>
<equitySwapInvolved>0</equitySwapInvolved>
</transactionCoding>
<transactionAmounts><transactionShares><value>1000</value>
</transactionShares>
<transactionPricePerShare><footnoteId id="F1"></footnoteId>
</transactionPricePerShare>
<transactionAcquiredDisposedCode><value>D</value>
</transactionAcquiredDisposedCode>
</transactionAmounts>
<postTransactionAmounts><sharesOwnedFollowingTransaction><value>26120</value>
</sharesOwnedFollowingTransaction>
</postTransactionAmounts>
<ownershipNature><directOrIndirectOwnership><value>D</value>
</directOrIndirectOwnership>
</ownershipNature>
</nonDerivativeTransaction>
<nonDerivativeHolding><securityTitle><value>Common Stock</value>
</securityTitle>
<postTransactionAmounts><sharesOwnedFollowingTransaction><value>7000</value>
</sharesOwnedFollowingTransaction>
</postTransactionAmounts>
<ownershipNature><directOrIndirectOwnership><value>I</value>
</directOrIndirectOwnership>
<natureOfOwnership><value>Trust</value>
</natureOfOwnership>
</ownershipNature>
</nonDerivativeHolding>
</nonDerivativeTable>
<derivativeTable></derivativeTable>
<footnotes><footnote id="F1">These shares were gifted, therefore, a price was not determined.</footnote>
</footnotes>
<ownerSignature><signatureName>Dale L. Young</signatureName>
<signatureDate>2003-10-16</signatureDate>
</ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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