X0303 4/A 2009-11-05 2009-11-06 0 0000090185 SIGMA ALDRICH CORP SIAL 0001201801 JULIEN DAVID 0 1 0 0 President, Supply Chain Common Stock, $1 Par Value 2009-11-05 4 M 0 22200 25.315 A 58729 D Common Stock, $1 Par Value 2009-11-05 4 M 0 5400 18.25 A 64129 D Common Stock, $1 Par Value 2009-11-05 4 M 0 7800 25.315 A 71929 D Common Stock, $1 Par Value 2009-11-05 4 M 0 3400 28.66 A 75329 D Common Stock, $1 Par Value 2009-11-05 4 S 0 22200 54.1314 D 53129 D Common Stock, $1 Par Value 2009-11-05 4 S 0 14000 54.5377 D 39129 D Common Stock, $1 Par Value 2009-11-05 4 F 1 7404 53.13 D 31725 D NQ Stock Option, Right to Buy 25.315 2009-11-05 4 M 0 22200 0 D 2003-05-07 2012-05-07 Common Stock, $1 Par Value 22200 0 D ISO Stock Option, Right to Buy 18.25 2009-11-05 4 M 0 5400 0 D 2001-11-13 2010-11-13 Common Stock, $1 Par Value 5400 0 D ISO Stock Option, Right to Buy 25.315 2009-11-05 4 M 0 7800 0 D 2003-05-07 2012-05-07 Common Stock, $1 Par Value 7800 0 D ISO Stock Option, Right to Buy 28.66 2009-11-05 4 M 0 3400 0 D 2005-05-04 2014-05-04 Common Stock, $1 Par Value 3400 0 D Share balance is as of transaction date 11/05/2009. Share balance as of 03/25/2010 is 33,375. Carrie Fields, Attorney in Fact 2010-03-25