X0306 4 2022-03-15 0 0001549084 EKSO BIONICS HOLDINGS, INC. EKSO 0001201619 SHERMAN STEVEN C/O EKSO BIONICS HOLDINGS, INC. 1414 HARBOUR WAY SOUTH, SUITE 1201 RICHMOND CA 94804 1 1 0 0 CEO & Chairman Common Stock 2022-03-15 4 S 0 5965 2.5999 D 610459 D Represents shares sold by the Reporting Person on March 15, 2022 to cover tax withholding obligations incurred upon the vesting and settlement of the first installment of a restricted stock unit award originally reported by the Reporting Person in Form 4 filed with the Commission on March 10, 2022. The sale price represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $2.5980 to $2.60, inclusive. The Company can provide the full information regarding the number of shares sold at each separate price upon further request. /s/ John F. Glenn, as Attorney-in-Fact 2022-03-17