<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2021-02-08</periodOfReport>

    <issuer>
        <issuerCik>0000068505</issuerCik>
        <issuerName>Motorola Solutions, Inc.</issuerName>
        <issuerTradingSymbol>MSI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001201232</rptOwnerCik>
            <rptOwnerName>BROWN GREGORY Q</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>MOTOROLA SOLUTIONS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>500 WEST MONROE</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60661</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chairman and CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

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            </securityTitle>
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                </transactionPricePerShare>
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                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>482</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F15"/>
            </exerciseDate>
            <expirationDate>
                <value>2021-02-22</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Motorola Solutions, Inc. - Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>482</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock Appreciation Right</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>38.04</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2021-02-09</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>M</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>61036</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F15"/>
            </exerciseDate>
            <expirationDate>
                <value>2021-02-22</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Motorola Solutions, Inc. - Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>61036</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>270657</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The exercise of these options and stock appreciation rights and sale of shares reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 17, 2020.</footnote>
        <footnote id="F2">Includes shares acquired under the Motorola Solutions Employee Stock Purchase Plan and through the reinvestment of dividends.</footnote>
        <footnote id="F3">$183.0873 is the weighted average sales price.  Prices for this transaction ranged from $182.8050 to 183.70.  The reporting person undertakes to provide upon request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.</footnote>
        <footnote id="F4">$182.5902 is the weighted average sales price.  Prices for this transaction ranged from $182.50 to 182.79.  The reporting person undertakes to provide upon request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.</footnote>
        <footnote id="F5">This represents the difference between the number of SARs exercised (119,196) and the number of shares issued as a result of the exercise (94,409).  The number of shares to be issued under a SAR exercise is determined by multiplying the number of SARs being exercised by the difference between the FMV on the date the SAR is exercised ($182.93) and the base price ($38.04).</footnote>
        <footnote id="F6">$183.1780 is the weighted average sales price.  Prices for this transaction ranged from $182.76 to 183.66.  The reporting person undertakes to provide upon request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.</footnote>
        <footnote id="F7">$182.5564 is the weighted average sales price.  Prices for this transaction ranged from 182.50 to $182.75.  The reporting person undertakes to provide upon request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.</footnote>
        <footnote id="F8">This represents the difference between the number of SARs exercised (61,036) and the number of shares issued as a result of the exercise (48,316).  The number of shares to be issued under a SAR exercise is determined by multiplying the number of SARs being exercised by the difference between the FMV on the date the SAR is exercised ($182.54) and the base price ($38.04).</footnote>
        <footnote id="F9">$183.3748 is the weighted average sales price.  Prices for this transaction ranged from 183.01 to $183.81.  The reporting person undertakes to provide upon request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.</footnote>
        <footnote id="F10">$182.7676 is the weighted average sales price.  Prices for this transaction ranged from 182.50 to $183.00  The reporting person undertakes to provide upon request by the Commission staff, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price.</footnote>
        <footnote id="F11">These shares are held in an irrevocable trust for the benefit of the reporting person's wife and children.  The reporting person's wife is trustee of this trust.</footnote>
        <footnote id="F12">These shares are held in a family trust for the benefit of the reporting person's children.  The reporting person is trustee of this trust.</footnote>
        <footnote id="F13">These shares are held in a non-exempt gift trust for the benefit of the reporting person's child.  The reporting person's wife is trustee of this trust.</footnote>
        <footnote id="F14">These shares are held in a non-exempt gift trust for the benefit of the reporting person's child.  The reporting person's wife is trustee of this trust.</footnote>
        <footnote id="F15">These options and stock appreciation rights vested in three equal annual installments beginning on February 22, 2012.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Kristin L. Kruska, on behalf of Gregory Q. Brown, Chairman and Chief Executive Officer (Power of Attorney on File)</signatureName>
        <signatureDate>2021-02-10</signatureDate>
    </ownerSignature>
</ownershipDocument>
