<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2016-10-01</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001669812</issuerCik>
        <issuerName>LSC Communications, Inc.</issuerName>
        <issuerTradingSymbol>LKSD</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001201002</rptOwnerCik>
            <rptOwnerName>HAMILTON JUDITH H</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O LSC COMMUNICATIONS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>35 WEST WACKER DRIVE</rptOwnerStreet2>
            <rptOwnerCity>CHICAGO</rptOwnerCity>
            <rptOwnerState>IL</rptOwnerState>
            <rptOwnerZipCode>60601</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>9027</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Restricted Stock Units</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F2"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stoack</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <footnoteId id="F2"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Does not include restricted stock units, which are reflected as beneficially-owned and reported as shares of common stock.  The number of restricted stock units over the LSC Communications, Inc. (&quot;LSC&quot;) common stock has not yet been determined, as restricted stock units over R. R. Donnelley &amp; Sons Company (&quot;RRD&quot;) common stock outstanding prior to October 1, 2016 will be converted into restricted stock units over the LSC common stock to give effect to the distribution by RRD of 80.75% of the common stock of each of LSC and Donnelley Financial Solutions, Inc. (&quot;DFS&quot;), which occurred on October 1, 2016 (collectively, the &quot;Spinoffs&quot;).  The number of restricted stock units over the LSC common stock will be determined after the date hereof pursuant to an equitable adjustment in the Separation and Distribution Agreement, dated as of September 14, 2016, by and among RRD, DFS and LSC.  The Reporting Person will amend this Form 3 when such information is available.</footnote>
        <footnote id="F2">These restricted stock units are reported in Table II because they may be paid by the Company in either stock or cash at its option. These restricted stock units are payable in shares of common stock or cash when the Reporting Person ceases to be a director. The number of restricted stock units over LSC common stock has not yet been determined, as restricted stock units over RRD common stock outstanding prior to October 1, 2016 will be converted into restricted stock units over the LSC common stock to give effect to the Spinoffs. The number of restricted stock units over the LSC common stock will be determined after the date hereof pursuant to an equitable adjustment in the Separation and Distribution Agreement. The Reporting Person will amend this Form 3 when such information is available.</footnote>
    </footnotes>

    <remarks>Judith H. Hamilton became a director of LSC Communications, Inc. on October 1, 2016. Exhibit Index Exhibit 24 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Suzanne S. Bettman, Suzanne S. Bettman, Attorney-In-Fact for Judith H. Hamilton</signatureName>
        <signatureDate>2016-10-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
