Balance Sheet Details - Property and Equipment, net (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2026	Sep. 30, 2025	Sep. 30, 2026	Sep. 30, 2025	Dec. 31, 2025
Property, Plant, and Equipment [Line Items]
Property and equipment	$ 61,330		$ 61,330		$ 58,266
Less: accumulated depreciation and amortization	(48,001)		(48,001)		(45,242)
Property and equipment, net	13,329		13,329		13,024
Total depreciation expense	1,136	$ 1,318	3,582	$ 3,778
Income Statement Location [Axis]: us-gaap:ResearchAndDevelopmentExpense
Property, Plant, and Equipment [Line Items]
Total depreciation expense	1,025	1,200	3,250	3,327
Income Statement Location [Axis]: us-gaap:SellingGeneralAndAdministrativeExpense
Property, Plant, and Equipment [Line Items]
Total depreciation expense	111	$ 118	332	$ 451
Laboratory equipment
Property, Plant, and Equipment [Line Items]
Property and equipment	38,474		38,474		38,943
Leasehold improvements
Property, Plant, and Equipment [Line Items]
Property and equipment	15,322		15,322		15,229
Computer equipment and software
Property, Plant, and Equipment [Line Items]
Property and equipment	2,577		2,577		2,556
Office equipment and furniture
Property, Plant, and Equipment [Line Items]
Property and equipment	1,188		1,188		1,133
Construction in progress
Property, Plant, and Equipment [Line Items]
Property and equipment	$ 3,769		$ 3,769		$ 405