Consolidated Statements of Cash Flows $ in Thousands	12 Months Ended
	Dec. 31, 2025 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)
Operating activities:
Net loss	$ (43,974)	$ (65,276)	$ (76,240)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	5,248	4,946	5,518
Reduction in the carrying amount of right-of-use assets	3,044	3,184	4,405
Stock-based compensation	9,624	13,087	9,971
Provision (recovery) for credit losses	(113)	97	(65)
Asset impairment and other charges	0	165	9,984
Impairment of investment in non-marketable securities	300	6,902	12,215
Equity securities earned from research and development activities	0	0	(213)
Non-cash interest expense	1,305	885	0
Amortization of discount on short-term investments	(1,234)	(1,380)	0
Other non-cash items	6	(4)	4
Changes in operating assets and liabilities:
Financial assets	8,507	1,252	20,247
Inventories	(19)	886	(656)
Prepaid expenses and other assets	(1,694)	893	(865)
Accounts payable	(1,286)	(2,567)	2,287
Accrued compensation and other accrued liabilities	(2,848)	1,982	(14,041)
Other long-term liabilities	(3,161)	(4,151)	(5,341)
Deferred revenue	6,919	(10,311)	(19,848)
Net cash used in operating activities	(19,376)	(49,410)	(52,638)
Investing activities:
Purchase of property and equipment	(4,471)	(4,305)	(4,418)
Proceeds from sale of property and equipment	5	87	751
Purchases of short-term investments	(57,158)	(90,235)	0
Proceeds from maturity of short-term investments	85,126	35,500	0
Proceeds from sale of short-term investments	0	1,973	0
Investment in non-marketable securities	0	0	(1,191)
Net cash provided by (used in) investing activities	23,502	(56,980)	(4,858)
Financing activities:
Proceeds from exercises of stock options	1,098	1,384	422
Proceeds from issuance of stock under employee stock purchase plan	505	646	0
Proceeds from issuance of common stock in connection with equity sales agreements	17,267	31,319	8,652
Costs incurred in connection with equity sales agreements	(836)	(1,706)	(503)
Proceeds from long-term debt	9,897	29,521	0
Payment of debt issuance costs	(3)	(642)	0
Taxes paid related to net share settlement of equity awards	0	0	(404)
Net cash provided by financing activities	27,928	60,522	8,167
Net increase (decrease) in cash, cash equivalents and restricted cash	32,054	(45,868)	(49,329)
Cash, cash equivalents and restricted cash at the beginning of the year	20,829	66,697	116,026
Cash, cash equivalents and restricted cash at the end of the year	52,883	20,829	66,697
Supplemental disclosure of cash flow information:
Interest paid	3,149	2,566	44
Income taxes paid	0	17	194
Supplemental non-cash investing and financing activities:
Capital expenditures incurred but not yet paid	31	566	1,068
Cash reconciliation:
Cash and cash equivalents	50,793	19,264	65,116
Restricted cash, current and non-current	2,090	1,565	1,581
Total cash, cash equivalents and restricted cash at the end of the period	$ 52,883	$ 20,829	$ 66,697