Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2025	Dec. 31, 2024	Dec. 31, 2023
Revenues:
Total revenues	$ 70,387	$ 59,345	$ 70,143
Costs and operating expenses:
Cost of product revenue	9,338	16,288	12,809
Research and development	52,307	46,263	58,885
Selling, general and administrative	47,074	55,148	53,250
Restructuring charges	3,407	0	3,284
Asset impairment and other charges	0	165	9,984
Total costs and operating expenses	112,126	117,864	138,212
Loss from operations	(41,739)	(58,519)	(68,069)
Interest income	2,625	3,670	4,172
Interest and other expense, net	(4,813)	(10,393)	(12,274)
Loss before income taxes	(43,927)	(65,242)	(76,171)
Provision for income taxes	47	34	69
Net loss	$ (43,974)	$ (65,276)	$ (76,240)
Net loss per share, basic (in dollars per share)	$ (0.50)	$ (0.89)	$ (1.12)
Net loss per share, diluted (in dollars per share)	$ (0.50)	$ (0.89)	$ (1.12)
Weighted average common stock shares used in computing net loss per share, basic (in shares)	87,142	73,408	68,131
Weighted average common stock shares used in computing net loss per share, diluted (in shares)	87,142	73,408	68,131
Product revenue
Revenues:
Total revenues	$ 26,028	$ 36,786	$ 42,906
Research and development revenue
Revenues:
Total revenues	$ 44,359	$ 22,559	$ 27,237