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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2025
Income Tax Disclosure [Abstract]  
Schedule of Loss Before Income Taxes, Domestic and Foreign
Our loss before provision for income taxes were as follows (in thousands): 
 Year Ended December 31,
 202520242023
United States$(43,908)$(65,231)$(76,169)
Foreign(19)(11)(2)
Loss before provision for income taxes$(43,927)$(65,242)$(76,171)
Schedule of Components of Provision for Income Taxes The components of the provision for income taxes are as follows (in thousands): 
 Year Ended December 31,
 202520242023
Current provision:
State$$(6)$27 
Foreign43 42 42 
Total current provision 50 36 69 
Deferred benefit:
Foreign(3)(2)— 
Total deferred benefit(3)(2)— 
Provision for income taxes$47 $34 $69 
Schedule of Reconciliation of Provision for Income Taxes Calculated at the Statutory Rate to Provision for Income Taxes The following table is a reconciliation of the U.S. federal statutory rate of 21% to our effective rate for the year ended December 31, 2025 in accordance with the guidance in ASU No. 2023-09 (in thousands, except percentages):
 Year Ended December 31, 2025
 $%
Provision for income taxes at U.S. federal statutory rate$(9,225)21.00 %
State and local income taxes, net of federal— — 
Foreign tax effects— 
Tax credits(1,295)2.95 
Changes in valuation allowance7,494 (17.06)
Nontaxable or nondeductible items:
   Stock-based compensation2,645 (6.02)
   Others242 (0.55)
Changes in unrecognized tax benefits180 (0.41)
Other adjustments(0.02)
Provision for income taxes$47 (0.11)%
The following table is a reconciliation of the provision for income taxes calculated at the statutory rate to our provision for income taxes for the years ended December 31, 2024 and 2023 in accordance with the guidance prior to the adoption of ASU No. 2023-09 (in thousands): 
 Year Ended December 31,
 20242023
Tax benefit at federal statutory rate$(13,701)$(15,995)
State taxes(3,133)(2,208)
Research and development credits(419)(925)
Foreign operations taxed at different rates— — 
Stock-based compensation1,930 1,967 
Other nondeductible items(108)438 
Executive compensation306 152 
Change in valuation allowance15,159 16,640 
Provision for income taxes$34 $69 
Schedule of Significant Components of Deferred Tax Assets and Liabilities
Significant components of our deferred tax assets and liabilities are as follows (in thousands): 
 December 31,
 20252024
Deferred tax assets:
Net operating losses$101,027 $82,925 
Credits19,682 17,660 
Deferred revenues256 48 
Stock-based compensation3,187 4,786 
Reserves and accruals2,506 2,650 
Property and Equipment131 830 
Intangible assets57 244 
Capital losses453 452 
R&D Capitalization20,637 28,471 
Unrealized gain/loss
Interest carryforward399 — 
Lease liability8,474 7,445 
Other assets4,788 4,362 
Total deferred tax assets:161,600 149,875 
Valuation allowance(153,803)(142,994)
Deferred tax liabilities:
Right-of-use assets(7,808)(6,895)
Total deferred tax liabilities:(7,808)(6,895)
Net deferred tax liabilities$(11)$(14)
Schedule of Federal, State and Foreign NOL Carryforwards and Federal Research and Development Tax Credits
The following table sets forth our federal, state and foreign NOL carryforwards and federal research and development tax credits as of December 31, 2025 (in thousands): 
 December 31, 2025
 AmountExpiration
Years
Net operating losses, federal$182,918 2026-2037
Net operating losses, federal$237,257 Do not expire
Net operating losses, state$196,540 2028-2045
Tax credits, federal$21,388 2025-2045
Tax credits, state$22,978 Do not expire
Schedule of Reconciliation of the Beginning and Ending Amount of Unrecognized Tax Benefits A reconciliation of the beginning and ending amount of unrecognized tax benefits is as follows (in thousands): 
 December 31,
 202520242023
Balance at beginning of year$21,618 $20,204 $18,571 
Additions based on tax positions related to current year2,243 1,332 2,164 
Additions to tax position of prior years138 82 — 
Reductions to tax position of prior years(130)— (531)
Balance at end of year$23,869 $21,618 $20,204