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Segment, Geographical and Other Revenue Information - Segment Reporting (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Segment Reporting Information [Line Items]        
Total revenues $ 34,470 $ 36,769 $ 108,215 $ 80,253
Cost of product revenue 9,786 6,867 29,577 15,403
Research and development 21,821 15,165 60,410 39,562
Selling, general and administrative 13,499 13,407 39,859 37,600
Total costs and operating expenses 45,106 35,439 129,846 92,565
Income (loss) from operations (10,636) 1,330 (21,631) (12,312)
Unallocated depreciation and amortization (1,405) (768) (3,961) (2,143)
Stock-based compensation 4,531 3,016 11,600 8,547
Performance Enzymes        
Segment Reporting Information [Line Items]        
Total revenues 31,146 32,584 100,774 68,397
Novel Biotherapeutics        
Segment Reporting Information [Line Items]        
Total revenues 3,324 4,185 7,441 11,856
Product revenue        
Segment Reporting Information [Line Items]        
Total revenues 28,042 28,731 93,376 53,674
Product revenue | Performance Enzymes        
Segment Reporting Information [Line Items]        
Total revenues 28,042 28,731 93,376 53,674
Product revenue | Novel Biotherapeutics        
Segment Reporting Information [Line Items]        
Total revenues 0 0 0 0
Research and development revenue        
Segment Reporting Information [Line Items]        
Total revenues 6,428 8,038 14,839 26,579
Research and development revenue | Performance Enzymes        
Segment Reporting Information [Line Items]        
Total revenues 3,104 3,853 7,398 14,723
Research and development revenue | Novel Biotherapeutics        
Segment Reporting Information [Line Items]        
Total revenues 3,324 4,185 7,441 11,856
Operating segments        
Segment Reporting Information [Line Items]        
Total revenues 34,470 36,769 108,215 80,253
Cost of product revenue 9,786 6,867 29,577 15,403
Research and development 20,637 14,520 57,112 37,821
Selling, general and administrative 4,679 4,137 13,496 11,346
Total costs and operating expenses 35,102 25,524 100,185 64,570
Income (loss) from operations (632) 11,245 8,030 15,683
Stock-based compensation 4,531 3,016 11,600 8,547
Operating segments | Performance Enzymes        
Segment Reporting Information [Line Items]        
Total revenues 31,146 32,584 100,774 68,397
Cost of product revenue 9,786 6,867 29,577 15,403
Research and development 6,782 5,670 19,833 17,172
Selling, general and administrative 3,791 3,306 11,208 9,294
Total costs and operating expenses 20,359 15,843 60,618 41,869
Income (loss) from operations 10,787 16,741 40,156 26,528
Stock-based compensation 1,382 1,228 4,151 3,337
Operating segments | Novel Biotherapeutics        
Segment Reporting Information [Line Items]        
Total revenues 3,324 4,185 7,441 11,856
Cost of product revenue 0 0 0 0
Research and development 13,855 8,850 37,279 20,649
Selling, general and administrative 888 831 2,288 2,052
Total costs and operating expenses 14,743 9,681 39,567 22,701
Income (loss) from operations (11,419) (5,496) (32,126) (10,845)
Stock-based compensation 414 272 1,182 767
Operating segments | Product revenue        
Segment Reporting Information [Line Items]        
Total revenues 28,042 28,731 93,376 53,674
Operating segments | Research and development revenue        
Segment Reporting Information [Line Items]        
Total revenues 6,428 8,038 14,839 26,579
Corporate, non-segment        
Segment Reporting Information [Line Items]        
Total costs and operating expenses (7,947) (8,097) (24,940) (24,431)
Unallocated depreciation and amortization (1,405) (794) (3,953) (2,220)
Income (loss) before income taxes (9,984) 2,354 (20,863) (10,968)
Stock-based compensation $ 2,735 $ 1,516 $ 6,267 $ 4,443