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Revenue Recognition (Tables)
3 Months Ended
Mar. 31, 2022
Revenue from Contract with Customer [Abstract]  
Disaggregation of revenue Segment information is as follows (in thousands):
Three Months Ended March 31, 2022Three Months Ended March 31, 2021
Performance EnzymesNovel BiotherapeuticsTotalPerformance EnzymesNovel BiotherapeuticsTotal
Major products and service:
       Product revenue$30,690 $— $30,690 $10,226 $— $10,226 
Research and development revenue2,409 2,241 4,650 4,003 3,803 7,806 
Total revenues$33,099 $2,241 $35,340 $14,229 $3,803 $18,032 
Primary geographical markets:
Americas
$2,553 $1,179 $3,732 $2,871 $2,058 $4,929 
EMEA
3,065 1,062 4,127 4,537 1,745 6,282 
APAC
27,481 — 27,481 6,821 — 6,821 
Total revenues$33,099 $2,241 $35,340 $14,229 $3,803 $18,032 
Contract with customer The following table presents balances of contract assets, unbilled receivables, contract costs, and contract liabilities (in thousands):
March 31, 2022December 31, 2021
Contract assets$9,751 $4,557 
Unbilled receivables$9,584 $8,558 
Contract costs$46 $56 
Contract liabilities: deferred revenue$5,068 $6,335 
We recognized the following revenues (in thousands):
Three Months Ended March 31,
Revenue recognized in the period for:20222021
Amounts included in contract liabilities at the beginning of the period:
Performance obligations satisfied$1,094 $862 
Changes in the period:
Changes in the estimated transaction price allocated to performance obligations satisfied in prior periods215 24 
Performance obligations satisfied from new activities in the period - contract revenue34,031 17,146 
Total revenues$35,340 $18,032 
Performance obligation, expected timing of satisfaction The following table includes estimated revenue expected to be recognized in the future related to performance obligations that are unsatisfied or partially unsatisfied at the end of the reporting periods. The estimated revenue does not include contracts with original durations of one year or less, amounts of variable consideration attributable to royalties, or contract renewals that are unexercised as of March 31, 2022.The balances in the table below are partially based on judgments involved in estimating future orders from customers subject to the exercise of material rights pursuant to respective contracts as of March 31, 2022 (in thousands):
Remainder of 2022
20232024
2025 and Thereafter
Total
Product revenue$60 $67 $100 $2,740 $2,967 
Research and development revenue1,254 847 — — 2,101 
Total revenues$1,314 $914 $100 $2,740 $5,068