Balance Sheet Details - Property and Equipment, net (Details) - USD ($) $ in Thousands	12 Months Ended
Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Property, Plant and Equipment, Net, by Type [Abstract]
Property and equipment	$ 57,227	$ 43,048
Less: accumulated depreciation and amortization	(35,882)	(33,373)
Property and equipment, net	21,345	9,675
Depreciation expense	3,113	1,950	$ 1,570
Laboratory equipment
Property, Plant and Equipment, Net, by Type [Abstract]
Property and equipment	33,101	25,468
Equipment retired during period	600	1,800
Leasehold improvements
Property, Plant and Equipment, Net, by Type [Abstract]
Property and equipment	16,117	10,785
Computer equipment and software
Property, Plant and Equipment, Net, by Type [Abstract]
Property and equipment	3,481	3,192
Office equipment and furniture
Property, Plant and Equipment, Net, by Type [Abstract]
Property and equipment	1,297	1,246
Construction in progress
Property, Plant and Equipment, Net, by Type [Abstract]
Property and equipment	$ 3,231	$ 2,357

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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The amount of expense recognized in the current period that reflects the allocation of the cost of tangible assets over the assets' useful lives. Includes production and non-production related depreciation.

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