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Basis of Presentation and Summary of Significant Accounting Policies (Tables)
12 Months Ended
Dec. 31, 2019
Accounting Policies [Abstract]  
Schedule of estimated ranges of useful lives of property and equipment
Property, equipment and leasehold improvements are stated at cost less accumulated depreciation and amortization and depreciated using the straight-line method over their estimated useful lives as follows:
Asset classificationEstimated useful life
Laboratory equipment5 years
Computer equipment and software
3 to 5 years
Office equipment and furniture5 years
Leasehold improvementsLesser of useful life or lease term
Property and equipment, net consisted of the following (in thousands): 
 December 31,
 20192018
Laboratory equipment (1)
$23,561  $21,328  
Leasehold improvements10,804  10,359  
Computer equipment and software3,016  3,954  
Office equipment and furniture1,461  1,272  
Construction in progress (2)
691  939  
Property and equipment39,533  37,852  
Less: accumulated depreciation and amortization(33,251) (33,093) 
Property and equipment, net$6,282  $4,759  
(1) Fully depreciated laboratory equipment with a cost of $1.0 million and $0.3 million were retired during the year ended December 31, 2019 and 2018, respectively.
(2) Construction in progress includes equipment received but not yet placed into service pending installation.
Impact of adoption on financial statements
In accordance with ASC 606, the disclosure of the impact of adoption to our consolidated statements of operations and balance sheets was as follows (in thousands, except per share amounts):

Year Ended December 31, 2018
As reportedAdjustmentsBalances without adoption of ASC 606
Revenues:
Product Revenue$25,590  $(3,422) $22,168  
Research and development revenue35,004  (1,609) 33,395  
Total revenues60,594  (5,031) 55,563  
Costs and operating expenses:
Cost of product revenue12,620(285) 12,335
Research and development29,978  (196) 29,782  
Selling, general and administrative29,291  —  29,291  
Total costs and operating expenses71,889  (481) 71,408  
Loss from operations(11,295) (4,550) (15,845) 
Interest income671  —  671  
Other expenses(291) —  (291) 
Loss before income taxes(10,915) (4,550) (15,465) 
Provision for (benefit from) income taxes(37) —  (37) 
Net loss$(10,878) $(4,550) $(15,428) 
Net loss per share, basic and diluted$(0.21) $(0.09) $0.30  
Weighted average common shares used in computing net loss per share, basic and diluted52,205  52,205  


December 31, 2018
As reportedAdjustmentsBalances without adoption of ASC 606
Assets
Accounts receivable$11,551  $(1,253) $10,298  
Unbilled receivables, current1,916  (1,916) —  
Contract assets35  (35) —  
Inventories5891590  
Unbilled receivables, non-current786(786) —  
Other non-current assets265  (42) 223  
Liabilities
Other accrued liabilities4,855  (520) 4,335  
Deferred revenue - current4,936  (1,574) 3,362  
Deferred revenue - non-current3,352  (1,445) 1,907  
Stockholders' equity
Accumulated deficit(330,474) (492) (330,966) 
The following table shows the reconciliation of ROU assets and lease obligations, with balances reflecting the adoption of ASC 842, related to both operating leases and finance leases and gives effect to the modified retrospective adoption and effective date method under the lease guidance on January 1, 2019 (in thousands):

Operating LeasesFinance Leases
Right-of-use assets, Balance at December 31, 2018$—  $—  
Changes in the period:
    Right-of-use assets created upon adoption of ASC 84226,617  493  
Right-of-use assets, balance at January 1, 2019$26,617  $493  
Lease obligations, balance at December 31, 2018$—  $—  
Changes in the period:
    Lease obligations created upon adoption of ASC 84227,562  302  
Lease obligations, balance at January 1, 2019$27,562  $302