Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended	6 Months Ended
Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Revenues:
Total revenues	$ 12,319	$ 13,538	$ 27,901	$ 27,580
Costs and operating expenses:
Cost of product revenue	2,772	2,611	7,163	6,436
Research and development	8,274	7,370	16,290	14,548
Selling, general and administrative	7,896	7,395	16,311	15,141
Total costs and operating expenses	18,942	17,376	39,764	36,125
Loss from operations	(6,623)	(3,838)	(11,863)	(8,545)
Interest income	220	174	450	245
Other expenses, net	(88)	(82)	(211)	(142)
Loss before income taxes	(6,491)	(3,746)	(11,624)	(8,442)
Provision for (benefit from) income taxes	16	(11)	19	(13)
Net loss	$ (6,507)	$ (3,735)	$ (11,643)	$ (8,429)
Net loss per share, basic and diluted (usd per share)	$ (0.12)	$ (0.07)	$ (0.21)	$ (0.17)
Weighted average common stock shares used in computing net loss per share, basic and diluted (shares)	54,954	52,787	54,564	50,598
Product Sales [Member]
Revenues:
Total revenues	$ 6,249	$ 3,723	$ 14,236	$ 9,886
Research and Development Revenue [Member]
Revenues:
Total revenues	$ 6,070	$ 9,815	$ 13,665	$ 17,694

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