Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
Mar. 31, 2019	Mar. 31, 2018
Revenues:
Total revenues	$ 15,583	$ 14,042
Costs and operating expenses:
Cost of product revenue	4,391	3,825
Research and development	8,016	7,178
Selling, general and administrative	8,415	7,746
Total costs and operating expenses	20,822	18,749
Loss from operations	(5,239)	(4,707)
Interest income	231	71
Other expenses, net	(125)	(60)
Loss before income taxes	(5,133)	(4,696)
Provision for (benefit from) income taxes	3	(2)
Net loss	$ (5,136)	$ (4,694)
Net loss per share, basic and diluted (usd per share)	$ (0.09)	$ (0.10)
Weighted average common stock shares used in computing net loss per share, basic and diluted (shares)	54,170	48,385
Product Sales [Member]
Revenues:
Total revenues	$ 7,988	$ 6,163
Research and Development Revenue [Member]
Revenues:
Total revenues	$ 7,595	$ 7,879

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